Metabolomics-a powerful tool in livestock research

被引:6
作者
Ashokan, M. [1 ,2 ,3 ]
Rana, Ekta [1 ]
Sneha, Kadimetla [2 ]
Namith, C. [1 ]
Naveen Kumar, G. S. [2 ]
Azharuddin, N. [1 ]
Elango, K. [1 ]
Jeyakumar, S. [1 ]
Ramesha, K. P. [1 ]
机构
[1] ICAR Natl Dairy Res Inst, Southern Reg Stn, Bangalore, Karnataka, India
[2] Hassan Vet Coll, Anim Genet & Breeding Div, Hassan, India
[3] Cattle Breeding & Fodder Dev, Dept Anim Husb, Thiruvarur, India
关键词
Metabolomics; nuclear magnetic resonance; mass spectrometry; pharmaco-metabolomics; nutri-metabolomics; NUCLEAR-MAGNETIC-RESONANCE; CHROMATOGRAPHY-QUADRUPOLE-TIME; SOMATIC-CELL COUNT; DAIRY-COWS; SERUM BIOMARKERS; GOAT MILK; COAGULATION PROPERTIES; GENETIC-PARAMETERS; PLASMA METABOLOME; BOVINE-MILK;
D O I
10.1080/10495398.2022.2128814
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Advancements in the Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) along with recent developments in omics sciences have resulted in a better understanding of molecular mechanisms and pathways associated with the physio-pathological state of the animal. Metabolomics is a post-genomics tool that deals with small molecular metabolites in a given set of time which provides clear information about the status of an organism. Recently many researchers mainly focus their research on metabolomics studies due to its valuable information in the various fields of livestock management and precision dairying. The main aim of the present review is to provide an insight into the current research output from different sources and application of metabolomics in various areas of livestock including nutri-metabolomics, disease diagnosis advancements, reproductive disorders, pharmaco-metabolomics, genomics studies, and dairy production studies. The present review would be helpful in understanding the metabolomics methodologies and use of livestock metabolomics in various areas in a brief way.
引用
收藏
页码:3237 / 3249
页数:13
相关论文
共 111 条
  • [21] Cheng JB, 2017, J DAIRY RES, V84, P401, DOI [10.1017/S0022029917000590, 10.1017/s0022029917000590]
  • [22] Clausen Morten R., 2011, BMC Physiology, V11, P14, DOI 10.1186/1472-6793-11-14
  • [23] Rumen fluid metabolomics of beef steers differing in feed efficiency
    Clemmons, Brooke A.
    Powers, Joshua B.
    Campagna, Shawn R.
    Seay, Taylor B.
    Embree, Mallory M.
    Myer, Phillip R.
    [J]. METABOLOMICS, 2020, 16 (02)
  • [24] Hemorrhagic shock and tissue injury drive distinct plasma metabolome derangements in swine
    Clendenen, Nathan
    Nunns, Geoffrey R.
    Moore, Ernest E.
    Reisz, Julie A.
    Gonzalez, Eduardo
    Peltz, Erik
    Silliman, Christopher C.
    Fragoso, Miguel
    Nemkov, Travis
    Wither, Matthew J.
    Hansen, Kirk
    Banerjee, Anirban
    Moore, Hunter B.
    D'Alessandro, Angelo
    [J]. JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2017, 83 (04) : 635 - 642
  • [25] Development of a metabolomic approach based on liquid chromatography-high resolution mass spectrometry to screen for clenbuterol abuse in calves
    Courant, Frederique
    Pinel, Gaud
    Bichon, Emmanuelle
    Monteau, Fabrice
    Antignac, Jean-Philippe
    Le Bizec, Bruno
    [J]. ANALYST, 2009, 134 (08) : 1637 - 1646
  • [26] Metabolomic Profiling in Cattle Experimentally Infected with Mycobacterium avium subsp paratuberculosis
    De Buck, Jeroen
    Shaykhutdinov, Rustem
    Barkema, Herman W.
    Vogel, Hans J.
    [J]. PLOS ONE, 2014, 9 (11):
  • [27] Metabolomics uncovers serum biomarkers that can predict the risk of retained placenta in transition dairy cows.
    Dervishi, E.
    Zhang, G.
    Mandal, R.
    Wishart, D. S.
    Ametaj, B. N.
    [J]. JOURNAL OF ANIMAL SCIENCE, 2017, 95 : 21 - 22
  • [28] GC-MS Metabolomics Identifies Metabolite Alterations That Precede Subclinical Mastitis in the Blood of Transition Dairy Cows
    Dervishi, Elda
    Zhang, Guanshi
    Dunn, Suzanna M.
    Mandal, Rupasri
    Wishart, David S.
    Ametaj, Burim N.
    [J]. JOURNAL OF PROTEOME RESEARCH, 2017, 16 (02) : 433 - 446
  • [29] Alterations in innate immunity reactants and carbohydrate and lipid metabolism precede occurrence of metritis in transition dairy cows
    Dervishi, Elda
    Zhang, Guanshi
    Hailemariam, Dagnachew
    Goldansaz, Seyed Ali
    Deng, Qilan
    Dunn, Suzanna M.
    Ametaj, Burim N.
    [J]. RESEARCH IN VETERINARY SCIENCE, 2016, 104 : 30 - 39
  • [30] Mass spectrometry-based metabolomics
    Dettmer, Katja
    Aronov, Pavel A.
    Hammock, Bruce D.
    [J]. MASS SPECTROMETRY REVIEWS, 2007, 26 (01) : 51 - 78