Quantitative study of droplet generation by pressure-driven microfluidic flows in a flow-focusing microdroplet generator

被引：4
作者：
Zeng, Wen [1 ]
Wang, Bohang [1 ]
Chang, Honglong [1 ]
Neuzil, Pavel [1 ]
机构：
[1] Northwestern Polytech Univ, Sch Mech Engn, Minist Educ, Key Lab Micro & Nano Syst Aerosp, 27 West Youyi Rd, Xian 710072, Shaanxi, Peoples R China
来源：
PHYSICS OF FLUIDS | 2024年 / 36卷 / 03期
基金：
中国国家自然科学基金;
关键词：
BUBBLES;
D O I：
10.1063/5.0191064
中图分类号：
O3 [力学];
学科分类号：
08 ; 0801 ;
摘要：
To precisely control the size of droplets is of great importance for the applications of the droplet microfluidics. In a flow-focusing microdroplet generator, the pressure-driven microfluidic device is designed to control the flow rates of the fluids. For a specific geometry of the flow-focusing microchannel, a mathematical model of droplet formation is established, and the nonlinear relation between the droplet length and the driven-pressure ratio can be described by our model. For pressure-driven microfluidic flows, the nonlinear relation between the droplet length and the driving-pressure ratio is measured experimentally in the flow-focusing microchannel. Particularly, by using the closed-loop control method of droplet generation, good agreements are shown between the measured size of droplets and the predicted size of the droplets. As a result, the control precision of the droplet size can be increased drastically by the closed-loop control method of droplet generation. Consequently, monodisperse droplets of extremely small size can be produced in the flow-focusing microdroplet generator.
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页数：7
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