Prevalence, types, and risk factors of functional gastrointestinal diseases in Hainan Province, China

被引:7
作者
Chen, Chen [1 ]
Zhang, Da-ya [1 ]
Chen, Shiju [1 ]
Huang, Shimei [1 ]
Zeng, Fan [1 ]
Li, Da [1 ]
Lv, Yan-ting [1 ]
Xiang, Xiaohong [2 ]
Chen, Run-xiang [1 ]
Zhang, Xiaodong [1 ]
Mao, Fengjiao [1 ]
Huang, Xianfeng [1 ]
Wang, Jun [3 ]
Bai, Feihu [4 ,5 ]
机构
[1] Hainan Med Univ, Grad Sch, Haikou 571199, Peoples R China
[2] Inner Mongolia Med Univ, Dept Pediat, Affiliated Chifeng Clin Coll, Chifeng 010110, Peoples R China
[3] Air Force Mil Med Univ, Hosp Xijing Hosp 986, Dept Gastroenterol, Xian 710054, Peoples R China
[4] Hainan Med Univ, Affiliated Hosp 2, Dept Gastroenterol, Yehai Ave 368, Haikou 570216, Hainan, Peoples R China
[5] Gastroenterol Clin Med Ctr Hainan Prov, Haikou 570216, Peoples R China
关键词
Functional gastrointestinal diseases; Prevalence; Risk factors; Hainan Province; China; IRRITABLE-BOWEL-SYNDROME; GLOBAL PREVALENCE; DISORDERS; GUT; SEROTONIN;
D O I
10.1038/s41598-024-55363-4
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
To investigate the prevalence, types, and risk factors of functional gastrointestinal diseases (FGIDs) in Hainan Province, China, in order to provide insights for future prevention and treatment strategies. A questionnaire survey was conducted from July 2022 to May 2023, using stratified sampling to sample local residents in five cities (20 townships) in Hainan Province. Out of 2057 local residents surveyed, 659 individuals (32.0%) reported experiencing at least one FGID. The most prevalent FGIDs were functional dyspepsia (FD) (10.7%), functional constipation (FC) (9.3%), irritable bowel syndrome (IBS) (6.8%), functional bloating (2.2%), belching disorder (2.2%), functional diarrhea (FDr) (1.5%), functional heartburn (1.5%), and fecal incontinence (0.98%). The study revealed significant associations between FGIDs and factors such as age, sleep quality, anxiety, smoking, alcohol consumption, and the consumption of pickled food (P < 0.05). Older age, poor sleep quality, anxiety, and the consumption of pickled food were identified as independent risk factors for the prevalence of FGIDs (P < 0.05). In Hainan Province, the overall prevalence of FGIDs was found to be 32.0%, with higher prevalences of FC and FD. Older age, poor sleep quality, anxiety, and the consumption of pickled food were identified as risk factors for FGIDs.
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页数:8
相关论文
共 51 条
[1]   Functional Constipation in Older Adults: Prevalence, Clinical Symptoms and Subtypes, Association with Frailty, and Impact on Quality of Life [J].
Arco, Sandra ;
Saldana, Esther ;
Serra-Prat, Mateu ;
Palomera, Elisabet ;
Ribas, Yolanda ;
Font, Sergi ;
Clave, Pere ;
Mundet, Lluis .
GERONTOLOGY, 2022, 68 (04) :397-406
[2]  
Balemans D, 2014, GASTROENTEROLOGY, V146, pS220
[3]   Gastrointestinal Symptoms and Channelopathy-Associated Epilepsy [J].
Beck, Veronica C. ;
Isom, Lori L. ;
Berg, Anne T. .
JOURNAL OF PEDIATRICS, 2021, 237 :41-+
[4]   Dysbiosis contributes to chronic constipation development via regulation of serotonin transporter in the intestine [J].
Cao, Hailong ;
Liu, Xiang ;
An, Yingying ;
Zhou, Guoqiong ;
Liu, Yanrong ;
Xu, Mengque ;
Dong, Wenxiao ;
Wang, Sinan ;
Yan, Fang ;
Jiang, Kui ;
Wang, Bangmao .
SCIENTIFIC REPORTS, 2017, 7
[5]   Potentiation of TRPV4 signalling by histamine and serotonin: an important mechanism for visceral hypersensitivity [J].
Cenac, Nicolas ;
Altier, Christophe ;
Motta, Jean-Paul ;
d'Aldebert, Emilie ;
Galeano, Sophie ;
Zamponi, Gerald W. ;
Vergnolle, Nathalie .
GUT, 2010, 59 (04) :481-488
[6]   A survey on Helicobacter pylori infection rate in Hainan Province and analysis of related risk factors [J].
Chen, Run-xiang ;
Zhang, Da-ya ;
Zhang, Xiaodong ;
Chen, Shiju ;
Huang, Shimei ;
Chen, Chen ;
Li, Da ;
Zeng, Fan ;
Chen, Jiajia ;
Mo, Cuiyi ;
Gao, Lei ;
Zeng, Juntao ;
Xiong, Jianxin ;
Chen, Zhai ;
Bai, Feihu .
BMC GASTROENTEROLOGY, 2023, 23 (01)
[7]   Gut Dysbiosis with Minimal Enteritis Induced by High Temperature and Humidity [J].
Chen, Song ;
Zheng, Yuhua ;
Zhou, Yiqing ;
Guo, Weizhong ;
Tang, Qin ;
Rong, Guangli ;
Hu, Weiwei ;
Tang, Jianbang ;
Luo, Huanhuan .
SCIENTIFIC REPORTS, 2019, 9 (1)
[8]   Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples From a Hong Kong Cohort: Systematic Review and Meta-analysis [J].
Cheung, Ka Shing ;
Hung, Ivan F. N. ;
Chan, Pierre P. Y. ;
Lung, K. C. ;
Tso, Eugene ;
Liu, Raymond ;
Ng, Y. Y. ;
Chu, Man Y. ;
Chung, Tom W. H. ;
Tam, Anthony Raymond ;
Yip, Cyril C. Y. ;
Leung, Kit-Hang ;
Fung, Agnes Yim-Fong ;
Zhang, Ricky R. ;
Lin, Yansheng ;
Cheng, Ho Ming ;
Zhang, Anna J. X. ;
To, Kelvin K. W. ;
Chan, Kwok-H ;
Yuen, Kwok-Y ;
Leung, Wai K. .
GASTROENTEROLOGY, 2020, 159 (01) :81-95
[9]   Dietary inclusion of nitrite-containing frankfurter exacerbates colorectal cancer pathology and alters metabolism in APCmin mice [J].
Crowe, William ;
Pan, Xiaobei ;
Mackle, James ;
Harris, Adam ;
Hardiman, Gary ;
Elliott, Christopher T. ;
Green, Brian D. .
NPJ SCIENCE OF FOOD, 2022, 6 (01)
[10]  
Daly M, 2022, LANCET, V399, P518, DOI 10.1016/S0140-6736(22)00187-8