Photoredox deoxygenative allylation of carboxylic acids via selective 1,6-addition of acyl radicals to electron-deficient 1,3-dienes

被引：12
作者：
Zhang, Lili [1 ]
Li, Yuhang [1 ]
Guo, Zhenyu [1 ]
Li, Yantao [1 ]
Li, Nian [1 ]
Li, Weipeng [1 ]
Zhu, Chengjian [1 ,2 ]
Xie, Jin [1 ]
机构：
[1] Nanjing Univ, Chem & Biomed Innovat Ctr ChemBIC, Sch Chem & Chem Engn, State Key Lab Coordinat Chem,Jiangsu Key Lab Adv O, Nanjing 210023, Jiangsu, Peoples R China
[2] Zhengzhou Univ, Coll Chem & Mol Engn, Green Catalysis Ctr, Zhengzhou 450001, Henan, Peoples R China
来源：
CHINESE JOURNAL OF CATALYSIS | 2023年 / 50卷
关键词：
Photoredox catalysis; Acyl radical; 3-Dienes; 6-Conjugate addition; 6-Dicarbonyl compound; 1,6-CONJUGATE ADDITION;
D O I：
10.1016/S1872-2067(23)64461-4
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
We report the 1,6-addition of acyl radicals to the electron-deficient 1,3-dienes under visible-light photoredox catalysis. The deoxygenative allylation of the carboxylic acid is achieved under mild conditions, generating the valuable 1,6-dicarbonyl compounds in moderate to good yields (up to 96%). A range of functionalized carboxylic acids are competent coupling partners. This deoxygenative allylation protocol has a high level of regio-and stereo-selectivity as well as good functional group comparability.& COPY; 2023, Dalian Institute of Chemical Physics, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：215 / 221
页数：7
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