Influences of sociodemographic characteristics and parental HPV vaccination hesitancy on HPV vaccination coverage in five US states

被引：14

作者：

Shato, T. ^{[1
,2
,3
]}

Humble, S. ^{[3
]}

Anandarajah, A. ^{[3
,4
,5
]}

Barnette, A. ^{[6
]}

Brandt, H. M. ^{[7
]}

Garbutt, J. ^{[8
]}

Klesges, L. ^{[3
]}

Thompson, V. S. ^{[4
,5
,8
]}

Silver, M. I. ^{[9
]}

机构：

[1] Washington Univ St Louis, Implementat Sci Ctr Canc Control, Brown Sch, One Brookings Dr,Campus Box 1196, St Louis, MO 63130 USA

[2] Washington Univ St Louis, Prevent Res Ctr, Brown Sch, One Brookings Dr,Campus Box 1196, St Louis, MO 63130 USA

[3] Washington Univ, Dept Surg, Div Publ Hlth Sci, Sch Med, St Louis, MO 63110 USA

[4] Barnes Jewish Hosp, Alvin J Siteman Canc Ctr, St Louis, MO 63110 USA

[5] Washington Univ, Sch Med, St Louis, MO 63110 USA

[6] St Francis Med Ctr, 211 St Francis Dr, Cape Girardeau, MO 63703 USA

[7] St Jude Childrens Res Hosp, HPV Canc Prevent Program, 262 Danny Thomas Pl, Memphis, TN 38105 USA

[8] Washington Univ, Dept Med & Pediat, Sch Med, St Louis, MO 63110 USA

[9] Washington Univ St Louis, Brown Sch, St Louis, MO 63130 USA

来源：

VACCINE | 2023年 / 41卷 / 25期

基金：

美国国家卫生研究院;

关键词：

HPV vaccine; HPV vaccine hesitancy; Adolescents; United States; HUMAN-PAPILLOMAVIRUS VACCINATION; RECOMMENDED IMMUNIZATION SCHEDULE; UNITED-STATES; ADVISORY-COMMITTEE; ADOLESCENTS; ASSOCIATION; PREVALENCE; COVID-19; YOUNGER; SERIES;

D O I：

10.1016/j.vaccine.2023.04.082

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Background: In the United States (US), half of new human papillomavirus (HPV) infections occur among young people aged 15-24 years. Despite the effectiveness of HPV vaccination in protecting against HPV-associated cancers, its coverage among adolescents remains suboptimal. This study examined the associ-ation of sociodemographic characteristics and HPV vaccination hesitancy with HPV vaccination coverage in five US states with disproportionately low adolescent coverage rates compared to the national average. Methods: Responses to an online Qualtrics survey from 926 parents of children aged 9-17 years in Arkansas, Mississippi, Missouri, Tennessee, and Southern Illinois in July 2021 were analyzed using multi-variate logistic regression to estimate the association of sociodemographic characteristics and HPV vacci-nation hesitancy with HPV vaccination coverage. Results: Of the parents, 78 % were female, 76 % were non-Hispanic White, 61.9 % lived in rural areas, 22 % were classified as HPV vaccine hesitant, and 42 % had vaccinated their oldest child between the ages of 9-17 years against HPV. Children of vaccine hesitant parents were less likely to have received any doses of the HPV vaccine than children of non-vaccine hesitant parents (AOR: 0.17, 95 % CI:0.11-0.27). Male chil-dren were less likely to have initiated the HPV vaccine series than female children (AOR: 0.70, 95 % CI:0.50- 0.97). Older children (13-17 vs 9-12 years), receiving the meningococcal conjugate or most recent seasonal influenza vaccine were all associated with higher likelihoods of receiving any doses of the HPV vaccine (AOR: 6.01, 95 % CI:3.98-9.08; AOR: 2.24, 95 % CI:1.27-3.95; AOR: 2.41, 95 % CI:1.73-3.36, respectively). Conclusions: Adolescent HPV vaccination coverage remains low in our targeted states. Children's age, sex, and parental vaccine hesitancy were significantly associated with likelihood of HPV vaccination. These find-ings offer the opportunity for targeted interventions among parents in regions with low vaccine uptake and underscore the importance of developing and implementing strategies to address parental HPV vaccination hesitancy to improve uptake in the US.& COPY; 2023 Elsevier Ltd. All rights reserved.

引用

页码：3772 / 3781

页数：10

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Allen A, 2020, M CHALL VACC HES

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