Decisional Regret in Long-Term Australian Allogeneic Hematopoietic Stem Cell Transplantation Survivors: A Cross-Sectional Survey

被引：1

作者：

McErlean, Gemma ^{[1
,2
,13
]}

Tapp, Caley ^{[3
,4
]}

Brice, Lisa ^{[5
]}

Pradhan, Anisha ^{[1
]}

Gilroy, Nicole ^{[2
,6
]}

Kabir, Masura ^{[7
]}

Greenwood, Matt ^{[5
,8
]}

Larsen, Stephen R. ^{[9
]}

Moore, John ^{[10
]}

Gottlieb, David ^{[6
,8
]}

Hertzberg, Mark ^{[11
]}

Brown, Louisa ^{[12
]}

Hogg, Megan ^{[6
]}

Huang, Gillian ^{[6
]}

Ward, Christopher ^{[5
,8
]}

Kerridge, Ian ^{[5
,8
]}

机构：

[1] Univ Wollongong, Sydney, NSW, Australia

[2] New South Wales Agcy Clin Innovat, Sydney, Australia

[3] Univ Queensland, Herston, Australia

[4] Queensland Ctr Mental Hlth Res, Wacol, Australia

[5] Royal North Shore Hosp, Sydney, NSW, Australia

[6] Westmead Hosp, Sydney, NSW, Australia

[7] Westmead Breast Canc Inst, Sydney, NSW, Australia

[8] Univ Sydney, Camperdown, NSW, Australia

[9] Royal Prince Alfred Hosp, Sydney, NSW, Australia

[10] St Vincents Hosp, Sydney, NSW, Australia

[11] Prince Wales Hosp, Randwick, NSW, Australia

[12] Calvary Mater Hosp, Newcastle, NSW, Australia

[13] Univ Wollongong, Fac Sci Med & Hlth, Sch Nursing, 1 Pitt St, Sydney, NSW 2232, Australia

来源：

CLINICAL NURSING RESEARCH | 2023年 / 32卷 / 08期

关键词：

decisional regret; psychosocial; bone marrow transplantation; hematopoietic stem cell transplant; survivorship; cancer; allogeneic transplant; QUALITY-OF-LIFE; ANXIETY STRESS SCALES; VERSUS-HOST-DISEASE; NEW-SOUTH-WALES; PROSTATE-CANCER; FUNCTIONAL ASSESSMENT; CLINICAL-TRIALS; BLOOD; DEPRESSION; HEALTH;

D O I：

10.1177/10547738231180337

中图分类号：

R47 [护理学];

学科分类号：

1011 ;

摘要：

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an intensive but effective treatment for malignant and non-malignant diseases. However, long-term survival often comes at a cost, with survivors experiencing chronic morbidity and are at risk of relapse and secondary malignancy. This study aimed to describe decisional regret in a large cohort of Australian long-term allo-HSCT survivors. A cross-sectional survey was conducted with 441 adults in New South Wales, assessing quality of life (QoL), psychological, social, demographic, and clinical variables. Less than 10% of survivors expressed regret, with chronic graft-versus-host disease being the most important clinical factor. Psycho-socioeconomic factors such as depression, lower QoL scores, lower household income, higher treatment burden, and not resuming sex post-HSCT were also associated with regret. Findings highlight the need for valid informed consent and ongoing follow-up and support for allo-HSCT survivors dealing with life post-transplant. Nurses and healthcare professionals play a critical role in addressing decisional regret in these patients.

引用

页码：1134 / 1144

页数：11

共 45 条

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[2]

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[3]

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