LSpECifying transgene expression

被引：0
作者：
Annoni, Andrea [1 ]
Cantore, Alessio [1 ,2 ]
机构：
[1] IRCCS San Raffaele Sci Inst, San Raffaele Telethon Inst Gene Therapy SR Tiget, Milan, Italy
[2] Univ Vita Salute San Raffaele, Milan, Italy
来源：
MOLECULAR THERAPY NUCLEIC ACIDS | 2024年 / 35卷 / 01期
关键词：
FACTOR-IX; LENTIVIRAL VECTORS; IMMUNE TOLERANCE; GENE-THERAPY; INDUCTION; ANTIGEN;
D O I：
10.1016/j.omtn.2024.102144
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页数：2
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共 20 条
[1]   GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions [J].
Agudo, Judith ;
Ruzo, Albert ;
Park, Eun Sook ;
Sweeney, Robert ;
Kana, Veronika ;
Wu, Meng ;
Zhao, Yong ;
Egli, Dieter ;
Merad, Miriam ;
Brown, Brian D. .
NATURE BIOTECHNOLOGY, 2015, 33 (12) :1287-+
[2]   Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs [J].
Akbarpour, Mahzad ;
Goudy, Kevin S. ;
Cantore, Alessio ;
Russo, Fabio ;
Sanvito, Francesca ;
Naldini, Luigi ;
Annoni, Andrea ;
Roncarolo, Maria Grazia .
SCIENCE TRANSLATIONAL MEDICINE, 2015, 7 (289)
[3]   Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice [J].
Annoni, Andrea ;
Cantore, Alessio ;
Della Valle, Patrizia ;
Goudy, Kevin ;
Akbarpour, Mahzad ;
Russo, Fabio ;
Bartolaccini, Sara ;
D'Angelo, Armando ;
Roncarolo, Maria Grazia ;
Naldini, Luigi .
EMBO MOLECULAR MEDICINE, 2013, 5 (11) :1684-1697
[4]   In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance [J].
Annoni, Andrea ;
Brown, Brian D. ;
Cantore, Alessio ;
Sergi, Lucia Sergi ;
Naldini, Luigi ;
Roncarolo, Maria-Grazia .
BLOOD, 2009, 114 (25) :5152-5161
[5]   A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice [J].
Brown, Brian D. ;
Cantore, Alessio ;
Annoni, Andrea ;
Sergi, Lucia Sergi ;
Lombardo, Angelo ;
Della Valle, Patrizia ;
D'Angelo, Armando ;
Naldini, Luigi .
BLOOD, 2007, 110 (13) :4144-4152
[6]   Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer [J].
Brown, Brian D. ;
Venneri, Mary Anna ;
Zingale, Anna ;
Sergi, Lucia Sergi ;
Naldini, Luigi .
NATURE MEDICINE, 2006, 12 (05) :585-591
[7]   INDUCTION OF IMMUNOLOGICAL TOLERANCE BY PORCINE LIVER ALLOGRAFTS [J].
CALNE, RY ;
SELLS, RA ;
PENA, JR ;
DAVIS, DR ;
MILLARD, PR ;
HERBERTSON, BM ;
BINNS, RM ;
DAVIES, DAL .
NATURE, 1969, 223 (5205) :472-+
[8]   HEPATIC SUPPRESSION OF SENSITIZATION TO ANTIGEN ABSORBED INTO PORTAL SYSTEM [J].
CANTOR, HM ;
DUMONT, AE .
NATURE, 1967, 215 (5102) :744-&
[9]   Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice [J].
Follenzi, A ;
Battaglia, M ;
Lombardo, A ;
Annoni, A ;
Roncarolo, MG ;
Naldini, L .
BLOOD, 2004, 103 (10) :3700-3709
[10]   Liver induced transgene tolerance with AAV vectors [J].
Keeler, Geoffrey D. ;
Markusic, David M. ;
Hoffman, Brad E. .
CELLULAR IMMUNOLOGY, 2019, 342
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