Tails don't tell the whole story

被引：0

作者：

Garcia-Marcos, Mikel ^{[1
,2
]}

机构：

[1] Boston Univ, Chobanian & Avedisian Sch Med, Dept Biochem & Cell Biol, Boston, MA 02115 USA

[2] Boston Univ, Coll Arts & Sci, Dept Biol, Boston, MA 02115 USA

来源：

STRUCTURE | 2023年 / 31卷 / 05期

关键词：

PROTEINS; COMPLEX;

D O I：

10.1016/j.str.2023.03.015

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Before engaging G protein-coupled receptors (GPCRs) to transduce extracellular signals, heterotrimeric G proteins (G alpha beta gamma) must fold properly with the help of chaperones. In this issue of Structure, Papasergi-Scott et al. (2023) unveil the molecular basis for how mammalian Ric-8 chaperones achieve selectivity for their respective G alpha subunit clients.

引用

页码：505 / 506

页数：2

共 20 条

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