A novel flexible electrode with highly stable trifluoroacetic acid modified Nb2CTx MXene for the sensitive detection of rifampicin

被引：15
作者：
Ankitha, Menon [1 ]
Shabana, Neermunda [1 ,2 ]
Vaishag, Pushpalatha V. [1 ,2 ]
Rasheed, Pathath Abdul [1 ,2 ]
机构：
[1] Indian Inst Technol Palakkad, Dept Chem, Palakkad 678557, Kerala, India
[2] Indian Inst Technol Palakkad, Dept Biol Sci & Engn, Palakkad 678557, Kerala, India
来源：
JOURNAL OF ELECTROANALYTICAL CHEMISTRY | 2023年 / 928卷
关键词：
Nb2CTx  MXene; Trifluoroacetic acid; Carbon cloth; Rifampicin; Anti-tuberculosis drug; Electrochemical sensor; ELECTROCATALYST; NANOPARTICLES; NANOSHEETS; EFFICIENT; NITROGEN;
D O I：
10.1016/j.jelechem.2022.117088
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In this work, we report the synthesis of highly stable trifluoroacetic acid (TFA) modified Nb2CTx MXene for the electrochemical detection of anti-tuberculosis drug rifampicin (RIF). The modification of Nb2CTx with TFA enhances the colloidal stability of Nb2CTx and the TFA@Nb2CTx based sensor was able to detect RIF from 100 pM to 1 mu M with a limit of detection of (LOD) of 4.8 pM. The developed sensor exhibited superior selec-tivity in addition to its practical applicability by using pharmaceutical drug sample and human serum samples. This work explores a novel engineering strategy to develop highly stable and aggregation free Nb2CTx MXene for different applications.
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页数：9
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