Maternal and Fetal Outcomes in Critically Ill Patients Infected with COVID-19: A Case Series

Introduction: Maternal mortality is a critical event. Maternal mortality rates over the last century had reduced significantly, at least until the COVID-19 pandemic. Methods: We retrospectively analyzed three pregnant women who succumbed to severe COVID-19. Results: Despite trying all available known therapies for COVID-19 at the time they presented, such as remdesivir, favipravir, steroid, hydroxychloroquine, pegylated interferon, N-acetyl cysteine, anticoagulants, prone positioning, mechanical ventilation, extracorporeal membrane oxygenation, and early delivery by cesarean, these young women in the reproductive age group could not be saved. Pregnancy was the factor that aggravated COVID-19 pneumonia. Although the patients were given extensive multidisciplinary care, they were not able to survive. However, all three neonates were delivered alive. Conclusion: Three cases of catastrophic fatal maternal outcomes occurred due to severe COVID-19 pneumonia, even though all available treatments were provided.