Pigmented Epidermotropic Breast Carcinoma: A Diagnostic Pitfall Mimicking Melanoma A Case Report and Literature Review

被引:1
作者
Rolim, Ines [1 ,2 ,6 ]
Rafael, Margarida [3 ]
Robson, Alistair [2 ,4 ]
Costa Rosa, Joaninha [2 ,5 ]
机构
[1] Fundacao Champalimaud, Anat Pathol, Lisbon, Portugal
[2] Inst Portugues Oncol Lisboa Francisco Gentil EPE, Pathol Dept, Lisbon, Portugal
[3] Inst Portugues Oncol LisboaFrancisco Gentil EPE, Dermatol Dept, Lisbon, Portugal
[4] Source LDPath, London, England
[5] Univ Nova Lisboa, Nova Med Sch, Pathol, Fac Ciencias Med, Lisbon, Portugal
[6] Fundacao Champalimaud, Anat Pathol, Ave Brasilia, P-1400038 Lisbon, Portugal
关键词
cutaneous metastatic disease; epidermotropic carcinoma; melanoma; MALIGNANT-MELANOMA; PAGET-DISEASE; METASTASIS; COLONIZATION; EXPRESSION;
D O I
10.1177/10668969231177702
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
We report the clinical and pathologic features of a patient with breast carcinoma, who developed clinically visible pigmented skin lesions during the course of the disease. The combination of clinical pigmentation, histological pagetoid epidermal spread, and considerable melanin pigment within tumour cells lead to a misdiagnosis of melanoma. This case provides a striking example of the ability of epidermotropic breast carcinoma to mimic melanoma. A literature review is also reported.
引用
收藏
页码:386 / 393
页数:8
相关论文
共 49 条
[1]   BREAST METASTASES FROM MALIGNANT-MELANOMA [J].
ARORA, R ;
ROBINSON, WA .
JOURNAL OF SURGICAL ONCOLOGY, 1992, 50 (01) :27-29
[2]   MELANOCYTE COLONIZATION AND PIGMENTATION OF BREAST CARCINOMA [J].
AZZOPARDI, JG ;
EUSEBI, V .
HISTOPATHOLOGY, 1977, 1 (01) :21-30
[3]   Metaplastic breast carcinoma with melanocytic differentiation [J].
Bendic, Antonia ;
Bozic, Maja ;
Durdov, Merica G. .
PATHOLOGY INTERNATIONAL, 2009, 59 (09) :676-680
[4]  
Bernardo M M, 1980, Acta Med Port, V2, P39
[5]   PIGMENTED EPIDERMOTROPIC METASTASIS OF A BREAST-CARCINOMA [J].
BOURLOND, A .
DERMATOLOGY, 1994, 189 :46-49
[6]  
CHUMAS JC, 1981, AM J SURG PATHOL, V5, P711, DOI 10.1097/00000478-198110000-00015
[7]   Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas [J].
Cimino-Mathews, Ashley ;
Subhawong, Andrea P. ;
Elwood, Hillary ;
Warzecha, Hind Nassar ;
Sharma, Rajni ;
Park, Ben Ho ;
Taube, Janis M. ;
Illei, Peter B. ;
Argani, Pedram .
HUMAN PATHOLOGY, 2013, 44 (06) :959-965
[8]   PIGMENTED EPIDERMOTROPIC DUCTAL CARCINOMA OF THE BREAST IN A MALE - ULTRASTRUCTURAL EVIDENCE OF MELANOCYTIC COLONIZATION AND MELANIN TRANSFER TO THE TUMOR [J].
FERNADEZFIGUERAS, MT ;
PUIG, L ;
CASANOVA, JM ;
MUSULEN, E ;
MATIASGUIU, X ;
NAVASPALACIOS, JJ .
JOURNAL OF CUTANEOUS PATHOLOGY, 1995, 22 (03) :276-280
[9]  
Gaitan-Gaona Francisco, 2016, Dermatol Online J, V22
[10]   Pigmented metastasis of breast carcinoma mimicking malignant melanoma [J].
García-F-Villalta, MJ ;
Adrados, M ;
Daudén, E ;
Fraga, J ;
García-Díezt, A .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2004, 18 (02) :223-224