Electroreductive Nickel-Catalyzed Allylation of Aryl Chlorides

被引：8
作者：
Fu, Xin [1 ]
Ran, Tingting [1 ]
Zhou, Yu [1 ]
Liu, Jie [2 ,3 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, Changsha 410082, Peoples R China
[2] Hunan Univ, Coll Chem & Chem Engn, Changsha 410082, Peoples R China
[3] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 88卷 / 09期
关键词：
CROSS-COUPLING REACTIONS; ELECTROCHEMICAL ALLYLATION; ALLYLIC SUBSTITUTION; ALKYL-HALIDES; METAL; LIGHT; DERIVATIVES; PHOTOREDOX; IODIDES;
D O I：
10.1021/acs.joc.2c02926
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein, we report a facile and efficient allylation via electrochemical promoted Ni-catalyzed reductive carbon-carbon bond formation. Readily available (hetero)aryl chlorides with a variety of allylic sulfones are used as electrophiles in this electroreductive coupling. This Nicatalyzed modular approach displays generally good functional group tolerance and broad substrate scope. This reaction allows a series of allylic compounds to be created including several structurally complex natural products and pharmaceutical motifs.
引用
收藏
页码：6132 / 6139
页数：8
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