Low-energy electron beam deposition of metal-containing organic-inorganic coatings with selective activity against microorganisms

被引:2
|
作者
Liu, Yiming [1 ,2 ]
Rogachev, A. V. [1 ,2 ]
Tan, Xiaoxue [1 ]
Rogachev, A. A. [1 ,3 ]
Jiang, Xiaohong [1 ]
Pyzh, A. E. [4 ]
Yarmolenko, V. A. [5 ]
Yarmolenko, M. A. [1 ,2 ]
Rudenkov, A. S. [1 ,2 ]
机构
[1] Nanjing Univ Sci & Technol, Int Chinese Belorussian Sci Lab Vacuum Plasma Tech, 200, Xiaolingwei St, Nanjing 210094, Peoples R China
[2] Francisk Skorina Gomel State Univ, 104, Sovetskaya St, Gomel 246019, BELARUS
[3] Natl Acad Sci Belarus, Inst Chem New Mat, 36F Skoriny, Minsk 220141, BELARUS
[4] Inst Physiol Natl Acad Sci Belarus, 28, Acad Skaya St, Minsk 220072, BELARUS
[5] Gomel State Med Univ, 5, Lange St, Gomel 246000, BELARUS
关键词
Surface modification; Composite coating; Electron beam deposition; C; albicans; E; coli; Lactobacillus rhamnosusGG; Molecular structure; RHAMNOSUS FTDC 8313; BACTERIAL VAGINOSIS; LACTOBACILLUS; PESSARY;
D O I
10.1016/j.vacuum.2022.111803
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The possibility of vacuum depositing complex metal-containing organic-inorganic coatings with selective stimulating and inhibitory activity against microorganisms (C. albicans, E. coli, Lactobacillus rhamnosus GG) has been demonstrated for the first time. The layer systems based on CaH2/Mg, citric acid, glucose, and ammonium phosphate were deposited with a low-energy electron beam. The features of chemical interlayer interactions, which result in the homogeneous layer formation, were considered. Interlayer interactions come from the absorption of atmospheric moisture by the coating. Other vacuum methods cannot produce such coatings. A comparative analysis of the calcium and magnesium effect on the ability to stimulate the growth of Lactobacillus rhamnosusGG was carried out. The resulting coatings can be used to modify the surface of pessaries.
引用
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页数:10
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