Numerical methods for control-based continuation of relaxation oscillations

被引:2
作者
Blyth, Mark [1 ]
Tsaneva-Atanasova, Krasimira [2 ,3 ,4 ]
Marucci, Lucia [1 ,5 ,6 ]
Renson, Ludovic [7 ]
机构
[1] Univ Bristol, Dept Engn Math, Bristol, England
[2] Univ Exeter, Hub Quantitat Modelling Healthcare, Exeter, England
[3] Alan Turing Inst, British Lib, London, England
[4] Univ Exeter, Data Sci Inst, Exeter, England
[5] Univ Bristol, BrisSynBio, Bristol, England
[6] Univ Bristol, Sch Cellular & Mol Med, Bristol, England
[7] Imperial Coll London, Dept Mech Engn, London, England
基金
英国工程与自然科学研究理事会;
关键词
Discretisation; Control-based continuation; Experimental bifurcation analysis; Relaxation oscillations; Bifurcation; Control; Phase constraints; BELOUSOV-ZHABOTINSKY REACTION; GENE-EXPRESSION; SYSTEMS; IDENTIFICATION; DYNAMICS; SPLINES; MODEL; APPROXIMATION; BIFURCATION; PLACEMENT;
D O I
10.1007/s11071-023-08288-y
中图分类号
TH [机械、仪表工业];
学科分类号
0802 ;
摘要
Control-based continuation (CBC) is an experimental method that can reveal stable and unstable dynamics of physical systems. It extends the path-following principles of numerical continuation to experiments and provides systematic dynamical analyses without the need for mathematical modelling. CBC has seen considerable success in studying the bifurcation structure of mechanical systems. Nevertheless, the method is not practical for studying relaxation oscillations. Large numbers of Fourier modes are required to describe them, and the length of the experiment significantly increases when many Fourier modes are used, as the system must be run to convergence many times. Furthermore, relaxation oscillations often arise in autonomous systems, for which an appropriate phase constraint is required. To overcome these challenges, we introduce an adaptive B-spline discretisation that can produce a parsimonious description of responses that would otherwise require many Fourier modes. We couple this to a novel phase constraint that phase-locks control target and solution phase. Results are demonstrated on simulations of a slow-fast synthetic gene network and an Oregonator model. Our methods extend CBC to a much broader range of systems than have been studied so far, opening up a range of novel experimental opportunities on slow-fast systems.
引用
收藏
页码:7975 / 7992
页数:18
相关论文
共 83 条
  • [1] A consistency analysis of phase-locked-loop testing and control-based continuation for a geometrically nonlinear frictional system
    Abeloos, G.
    Mueller, F.
    Ferhatoglu, E.
    Scheel, M.
    Collette, C.
    Kerschen, G.
    Brake, M. R. W.
    Tiso, P.
    Renson, L.
    Krack, M.
    [J]. MECHANICAL SYSTEMS AND SIGNAL PROCESSING, 2022, 170
  • [2] Experimental Characterization of Superharmonic Resonances Using Phase-Lock Loop and Control-Based Continuation
    Abeloos, Gaetan
    Volvert, Martin
    Kerschen, Gaetan
    [J]. NONLINEAR STRUCTURES & SYSTEMS, VOL 1, 2023, : 131 - 133
  • [3] Control-based continuation: Bifurcation and stability analysis for physical experiments
    Barton, David A. W.
    [J]. MECHANICAL SYSTEMS AND SIGNAL PROCESSING, 2017, 84 : 54 - 64
  • [4] Beregi S., 2021, ARXIV
  • [5] Bureau E, 2012, PROCEEDINGS OF THE ASME INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE 2012, VOL 1, PTS A AND B, P999
  • [6] A model of periodic oscillation for genetic regulatory systems
    Chen, LN
    Aihara, K
    [J]. IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-REGULAR PAPERS, 2002, 49 (10) : 1429 - 1436
  • [7] Optogenetic tools for microbial synthetic biology
    Chia, Natalie
    Lee, Sang Yup
    Tong, Yaojun
    [J]. BIOTECHNOLOGY ADVANCES, 2022, 59
  • [8] Cox M. G., 1972, Journal of the Institute of Mathematics and Its Applications, V10, P134
  • [9] De Boor C., 1978, A practical guide to splines
  • [10] Control-Based Continuation: A New Approach to Prototype Synthetic Gene Networks
    de Cesare, Irene
    Salzano, Davide
    di Bernardo, Mario
    Renson, Ludovic
    Marucci, Lucia
    [J]. ACS SYNTHETIC BIOLOGY, 2022, : 2300 - 2313