Selective Fluorosulfonylation of Thianthrenium Salts Enabled by Electrochemistry

被引：52

作者：

Kong, Xianqiang ^{[1
]}

Chen, Yiyi ^{[1
]}

Liu, Qianwen ^{[1
]}

Wang, WenJie ^{[1
]}

Zhang, Shuangquan ^{[1
]}

Zhang, Qian ^{[1
]}

Chen, Xiaohui ^{[1
]}

Xu, Yuan-Qing ^{[2
]}

Cao, Zhong-Yan ^{[2
]}

机构：

[1] Changzhou Inst Technol, Sch Chem Engn & Mat, Changzhou 213032, Peoples R China

[2] Henan Univ, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China

来源：

ORGANIC LETTERS | 2023年 / 25卷 / 04期

关键词：

SUFEX CLICK CHEMISTRY; SULFONYL FLUORIDES; GREEN;

D O I：

10.1021/acs.orglett.2c03956

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical electrochemically driven method for fluorosul-fonylation of both aryl and alkyl thianthrenium salts has been disclosed. The strategy does not need external redox reagents or metal catalysts. In combination with C-H thianthrenation of aromatics, this method provides a new tool for the site-selective fluorosulfonylation of drugs.

引用

页码：581 / 586

页数：6

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