The role of circular RNAs in the pathophysiology of oral squamous cell carcinoma

被引:20
作者
Sufianov, Albert [1 ,2 ]
Begliarzade, Sema [3 ]
Kudriashov, Valentin [4 ]
Beilerli, Aferin [5 ]
Ilyasova, Tatiana [6 ]
Liang, Yanchao [7 ]
Beylerli, Ozal [1 ,8 ]
机构
[1] PeoplesFriendship Univ Russia, RUDN Univ, Educ & Sci Inst Neurosurg, Moscow, Russia
[2] Sechenov First Moscow State Med Univ, Sechenov Univ, Dept Neurosurg, Moscow, Russia
[3] Republican Clin Perinatal Ctr, Ufa 450106, Russia
[4] Sichuan Univ, West China Hosp, Gastr Canc Ctr, Chengdu, Peoples R China
[5] Tyumen State Med Univ, Dept Obstet & Gynecol, 54 Odesskaya St, Tyumen 625023, Russia
[6] Bashkir State Med Univ, Dept Internal Dis, Ufa 450008, Russia
[7] Harbin Med Univ, Affiliated Hosp 1, Dept Neurosurg, Harbin 150001, Peoples R China
[8] Peoples Friendship Univ Russia, RUDN Univ, 6 Miklukho Maklaya St, Moscow 117198, Russia
来源
NON-CODING RNA RESEARCH | 2023年 / 8卷 / 01期
关键词
Non-coding RNAs; Circular RNAs; Biology function; Oral squamous cell carcinoma; Biomarker; PROGNOSTIC MARKER; HEPATOCELLULAR-CARCINOMA; REGULATORY NETWORKS; CANCER; PROLIFERATION; EXPRESSION; INITIATION; PROGRESSION; APOPTOSIS;
D O I
10.1016/j.ncrna.2022.11.004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Circular RNAs are non-coding RNAs that widely exist in eukaryotes. The research progress of its generation mechanism and biological function show that circular RNAs may be used in the development of tumors, neurological diseases, cardiovascular diseases. They play an important role in the occurrence and development of diseases and has a potential to be used as a disease marker. Oral squamous cell carcinoma is one of the most common malignant tumors in oral surgery. It is difficult to treat, easy to metastasize, and has a poor prognosis. Due to its unclear mechanism, blocking oral squamous cell carcinoma at the genetic level cannot be achieved. The research progress of circular RNA in the field of oral squamous cell carcinoma will bring new ideas for the biological treatment of oral squamous cell carcinoma. This review summarizes the circRNAs mechanism, the biological function and the research progress in the development of tumors, especially oral squamous cell carcinoma.
引用
收藏
页码:109 / 114
页数:6
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