A risk score to predict 30-day hospital readmission rate in cirrhotic patients with spontaneous bacterial peritonitis

被引:5
作者
Mousa, Nasser [1 ,2 ]
Abdel-Razik, Ahmed [1 ]
Elbaz, Sherif [3 ]
Salah, Mohamed [1 ]
Abdelaziz, Mohammed [1 ]
Habib, Alaa [4 ]
Deib, Ahmed [4 ]
Gadallah, Abdel-Naser [5 ]
El-wakeel, Niveen [6 ]
Eldars, Waleed [6 ,7 ]
Effat, Narmin [8 ]
El-Emam, Ola [8 ]
Taha, Khaled [4 ]
Elmetwalli, Alaa [9 ]
Mousa, Eman [10 ]
Elhammady, Dina [1 ]
机构
[1] Mansoura Univ, Trop Med Dept, Mansoura, Egypt
[2] Damietta Cardiol & Gastroenterol Ctr, Dumyat, Egypt
[3] Aswan Univ, Endem Dis & Gastroenterol Dept, Aswan, Egypt
[4] Mansoura Univ, Internal Med Dept, Mansoura, Egypt
[5] Menuofia Univ, Internal Med Dept, Menuofia, Egypt
[6] Mansoura Univ, Med Microbiol & Immunol Dept, Mansoura, Egypt
[7] New Mansoura Univ, Fac Med, Dept Basic Med Sci, Mansoura, Egypt
[8] Mansoura Univ, Clin Pathol Dept, Mansoura, Egypt
[9] Hosp ELRIAH, Egyptian Liver Res Inst & Hosp ELRIAH, Dept Clin Trial Res Unit & Drug Discovery, Mansoura, Egypt
[10] Mansoura Univ, Fac Dent, Mansoura, Egypt
关键词
Spontaneous bacterial peritonitis; 30-day readmission rate; Liver cirrhosis; CHRONIC LIVER-FAILURE; DECOMPENSATED CIRRHOSIS; HEPATORENAL-SYNDROME; MANAGEMENT; ASCITES; INFECTIONS; GUIDELINES; MORTALITY;
D O I
10.1186/s40001-023-01126-2
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background and aimThere is lack of 30-day hospital readmission prediction score in patients with liver cirrhosis and SBP. The aim of this study is to recognize factors capable of predicting 30-day readmission and to develop a readmission risk score in patients with SBP.MethodsThis study prospectively examined the 30-day hospital readmission for patients previously discharged with a diagnosis of SBP. Based on index hospitalization variables, a multivariable logistic regression model was implemented to recognize predictors of patient hospital readmission within 30 days. Consequently, Mousa readmission risk score was established to predict 30-day hospital readmission.ResultsOf 475 patients hospitalized with SBP, 400 patients were included in this study. The 30-day readmission rate was 26.5%, with 16.03% of patients readmitted with SBP. Age >= 60, MELD > 15, serum bilirubin > 1.5 mg/dL, creatinine > 1.2 mg/dL, INR > 1.4, albumin < 2.5 g/dL, platelets count <= 74 (10(3)/dL) were found to be independent predictors of 30-day readmission. Incorporating these predictors, Mousa readmission score was established to predict 30-day patient readmissions. ROC curve analysis demonstrated that at a cutoff value >= 4, Mousa score had optimum discriminative power for predicting the readmission in SBP with sensitivity 90.6% and specificity 92.9%. However, at cutoff value >= 6 the sensitivity and specificity were 77.4% and 99.7%, respectively, while a cutoff value >= 2 had sensitivity of 99.1% and specificity of 31.6%.ConclusionsThe 30-day readmission rate of SBP was 25.6%. With the suggested simple risk assessment Mousa score, patients at high risk for early readmission can be easily identified so as to possibly prevent poorer outcomes.
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页数:10
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