Blue light-emitting diodes for the treatment of localized vitiligo: A retrospective study

被引:5
作者
Lodi, Giuseppe [1 ,2 ]
Del Re, Chiara [3 ]
Nistico, Steven Paul [3 ]
Bennardo, Luigi [3 ]
Cannarozzo, Giovanni [1 ]
Sannino, Mario [1 ]
机构
[1] Univ Roma Tor Vergata, Laser Unit, Rome, Italy
[2] Univ Campania, Unit Dermatol, Naples, Italy
[3] Magna Graecia Univ Catanzaro, Dept Hlth Sci, Viale Europa SNC, I-88100 Catanzaro, CZ, Italy
关键词
blue light; light emitting diode (LED); vitiligo; PATHOGENESIS; PATIENT;
D O I
10.1111/jocd.15567
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
BackgroundVitiligo is an autoimmune dermatological disease characterized by hypopigmented macules.Treatments include topical agents, phototherapy, and laser therapies. Different lasers should be individually chosen regarding location, extent, activity of the disease. AimsThis article aims to demonstrate how blue LED is effective and safe, as its wavelength is very close to the UV spectrum (415 nm vs. 400 nm), but, unlike UV therapy, blue LED have not shown any long-term cancerogenic side effects. Patients/MethodsWe treated 30 patients affected by vitiligo localized on different anatomical areas with blue light-emitting diodes. ResultsComplete repigmentation occurred in 75.33% of treated patients (22 out of 30 patients, 14 males, and 8 females). Partial repigmentation occurred in the remaining patients. ConclusionsBlue LED light may be a safe and well-tolerated way to induce repigmentation in patients affected by vitiligo.
引用
收藏
页码:1273 / 1278
页数:6
相关论文
共 21 条
[1]   UVA1 Laser in the Treatment of Vitiligo [J].
Babino, Graziella ;
Giunta, Alessandro ;
Esposito, Maria ;
Saraceno, Rosita ;
Pavlidis, Athanasios ;
Del Duca, Ester ;
Chimenti, Sergio ;
Nistico, Steven Paul .
PHOTOMEDICINE AND LASER SURGERY, 2016, 34 (05) :200-204
[2]  
Baldo A, 2014, GIORN ITAL DERMAT V, V149, P123
[3]   Vitiligo: A Review [J].
Bergqvist, Christina ;
Ezzedine, Khaled .
DERMATOLOGY, 2020, 236 (06) :571-592
[4]   Photochemical reaction to increase melanogenesis using Buddleja officinalis and blue light-emitting diode irradiation in B16F10 [J].
Cho, Hyejoung ;
Kim, Byunggook ;
Kim, Ok-Su ;
Kim, Young ;
Yang, Ying ;
Song, Jianan ;
Liu, Danyang ;
Jeon, Sangmi ;
Kim, Okjoon .
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2021, 35
[5]   Tofacitinib Citrate for the Treatment of Vitiligo A Pathogenesis-Directed Therapy [J].
Craiglow, Brittany G. ;
King, Brett A. .
JAMA DERMATOLOGY, 2015, 151 (10) :1110-1112
[6]   JAK inhibitors in dermatology: The promise of a new drug class [J].
Damsky, William ;
King, Brett A. .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2017, 76 (04) :736-744
[7]   A Practical Approach to the Diagnosis and Treatment of Vitiligo in Children [J].
Ezzedine, Khaled ;
Silverberg, Nanette .
PEDIATRICS, 2016, 138 (01)
[8]   Vitiligo: Mechanisms of Pathogenesis and Treatment [J].
Frisoli, Michael L. ;
Essien, Kingsley ;
Harris, John E. .
ANNUAL REVIEW OF IMMUNOLOGY, VOL 38, 2020, 38 :621-648
[9]   Photobiomodulation: The Clinical Applications of Low-Level Light Therapy [J].
Glass, Graeme Ewan .
AESTHETIC SURGERY JOURNAL, 2021, 41 (06) :723-738
[10]   Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA) [J].
Harris, John E. ;
Rashighi, Mehdi ;
Nhan Nguyen ;
Jabbari, Ali ;
Ulerio, Grace ;
Clynes, Raphael ;
Christiano, Angela M. ;
Mackay-Wiggan, Julian .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2016, 74 (02) :370-371