Adverse health effects of emerging contaminants on inflammatory bowel disease

被引:28
作者
Chen, Xuejie [1 ,2 ]
Wang, Sidan [1 ,2 ]
Mao, Xueyi [3 ]
Xiang, Xin [3 ]
Ye, Shuyu [1 ,2 ]
Chen, Jie [1 ,4 ]
Zhu, Angran [3 ]
Meng, Yifei [3 ]
Yang, Xiya [3 ]
Peng, Shuyu [3 ]
Deng, Minzi [1 ,2 ]
Wang, Xiaoyan [1 ,2 ]
机构
[1] Cent South Univ, Xiangya Hosp 3, Dept Gastroenterol, Changsha, Hunan, Peoples R China
[2] Hunan Key Lab Nonresolving Inflammat & Canc, Changsha, Hunan, Peoples R China
[3] Cent South Univ, Xiangya Sch Med, Changsha, Hunan, Peoples R China
[4] Zhejiang Univ, Ctr Global Hlth, Hangzhou, Peoples R China
基金
中国国家自然科学基金;
关键词
inflammatory bowel disease; emerging contaminant (EC); exposome; adverse health effects (AHEs); gut dysbiosis; POLYCHLORINATED-BIPHENYLS PCBS; HEAVY-METALS; GUT MICROBIOTA; OXIDATIVE STRESS; HUMAN EXPOSURE; POLYSTYRENE NANOPARTICLES; INTESTINAL INFLAMMATION; ORGANIC POLLUTANTS; PRENATAL EXPOSURE; ARSENIC EXPOSURE;
D O I
10.3389/fpubh.2023.1140786
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Inflammatory bowel disease (IBD) is becoming increasingly prevalent with the improvement of people's living standards in recent years, especially in urban areas. The emerging environmental contaminant is a newly-proposed concept in the progress of industrialization and modernization, referring to synthetic chemicals that were not noticed or researched before, which may lead to many chronic diseases, including IBD. The emerging contaminants mainly include microplastics, endocrine-disrupting chemicals, chemical herbicides, heavy metals, and persisting organic pollutants. In this review, we summarize the adverse health effect of these emerging contaminants on humans and their relationships with IBD. Therefore, we can better understand the impact of these new emerging contaminants on IBD, minimize their exposures, and lower the future incidence of IBD.
引用
收藏
页数:18
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