Actinomyces meyeri Causing Cerebral Abscess in a Patient on Methotrexate: A Rare Case Report and Systematic Review of the Literature

被引：0

作者：

Verrienti, Giulio ^{[1
]}

Megliola, Gianluigi ^{[1
]}

Antonaci, Emanuele ^{[1
]}

Gisotti, Armando ^{[2
]}

Raccagni, Cecilia ^{[3
,4
]}

机构：

[1] Casa Cura Villa Verde, Neurorehabil, Lecce, Italy

[2] Osped L Bonomo, Anesthesia & Crit Care, Andria, Italy

[3] Prov Hosp, Neurol, Bolzano, Italy

[4] Lehrkrankenhaus Paracelsus Med Privatuniv, Neurol, Bolzano, Italy

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 06期

关键词：

anaerobic brain abscess; rheumatoid; oral methotrexate; actinomyces meyeri; immunocompromised brain abscess; BRAIN-ABSCESS; MANIFESTATIONS; DISEASE;

D O I：

10.7759/cureus.41204

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Central nervous system (CNS) actinomycosis is a rare, serious, life-threatening, suppurative infection caused by Actinomyces species. Actinomyces are anaerobic Gram-positive bacteria, which can be normally isolated from the polymicrobial flora of the gastrointestinal- and genital tracts. They are considered very low virulent bacteria to humans. However, they can lead to several types of local or disseminated infections, if certain pathologic states or immunodeficiency occur. Intracranial abscesses caused by Actinomyces meyeri are rarely reported in adults. In this case report, we describe a 66-year-old woman who presented to the emergency department due to progressive complaints of altered sensorium and low-grade fever, due to an A. meyeri-related brain abscess. The only risk factor was represented by immunodeficiency due to the therapy with Methotrexate and steroids.

引用

页数：8

共 20 条

[1] A rare case of voluminous brain abscess due to Actinomyces meyeri and Aggregatibacter aphrophilus: is there any evidence for a prolonged antibiotic oral relay?* [J].