Complementary administration of curcumin in PCOS: a systematic review

被引：0

作者：

Venkatesan, Kirthika ^{[1
]}

Menon, Sukrita ^{[2
]}

Firoz, Irene N. ^{[3
]}

Narendrula, Rashmi ^{[4
]}

Kunnath, Jafrikh T. ^{[5
]}

Kalapurakal, Ann M. ^{[6
]}

Ashok, Anuja ^{[7
]}

Iqbal, Anoop M. ^{[8
]}

Haroon, Nisha N. ^{[9
,10
]}

机构：

[1] Caribbean Med Univ, Sch Med, Willemstad, Curacao

[2] Amala Inst Med Sci, Amalanagar, India

[3] Royal Coll Surgeons Ireland, Sch Med, Dublin, Ireland

[4] Northern Ontario Sch Med, Sudbury, ON, Canada

[5] Govt Med Coll, Kozhikode, India

[6] Amer Univ Antigua, Osbourn, Antigua & Barbu

[7] Govt TD Med Coll, Vandanam, India

[8] Univ Wisconsin, Marshfield Childrens Hosp, Dept Pediat Endocrinol, Madison, WI USA

[9] Northern Ontario Sch Med, Dept Endocrinol & Internal Med, Sudbury, ON P3E 2C6, Canada

[10] Northern Ontario Sch Med, Div Clin Sci, Sudbury, ON, Canada

来源：

MINERVA OBSTETRICS AND GYNECOLOGY | 2023年 / 75卷 / 04期

关键词：

K ey words; Curcuma; Polycystic ovarian syndrome; Curcumin; POLYCYSTIC-OVARY-SYNDROME; ACTIVATED RECEPTOR-GAMMA; PEROXISOME PROLIFERATOR; DOUBLE-BLIND; EXPRESSION; WOMEN; INSULIN; LIVER; SERUM; GENE;

D O I：

10.23736/S2724-606X.22.05129-6

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

INTRODUCTION: The clinical benefit of curcumin, the active ingredient in turmeric, among women diagnosed with polycystic ovarian syndrome (PCOS) is unclear. In this systematic review, we aim to provide a brief review of the existing literature on the association between curcumin supplementation and PCOS. EVIDENCE ACQUISITION: Published articles relevant to the topic was obtained through extensive search using rel-evant keywords such as "polycystic ovarian syndrome," "PCOS," "turmeric," and "curcumin." Inclusion criteria included studies that investigated PCOS and turmeric/curcumin, while studies that investigated the use of curcumin in other gyne-cological disorders, infertility, rodent studies, and non-RCTs were excluded. EVIDENCE SYNTHESIS: A total of 14 articles were found and only five studies were incorporated based on the exclu-sion criteria. The main findings were that curcumin supplementation aids in improvement of lipid and glycemic profiles, Body Mass Index (BMI) and lowers androgen levels associated with PCOS. CONCLUSIONS: We shed light on additional therapeutic management for PCOS other than the conventional treatment. Further studies are required with larger sample sizes and diverse patient population to derive definitive conclusions re-garding benefits of curcumin supplementation in PCOS.

引用

页码：379 / 386

页数：8

共 34 条

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