Designer proteins as potential therapeutic biomolecular condensates

被引:0
|
作者
Ng, Tin Long Chris [1 ]
Hoare, Mateo [1 ]
Welsh, Timothy [2 ]
Tomas, Sneideris [2 ]
Wilde, Ellis [1 ]
Knowles, Tuomas P. J. [2 ]
Itzhaki, Laura S. [1 ]
Kumita, Janet R. [1 ]
机构
[1] Univ Cambridge, Dept Pharmacol, Cambridge, England
[2] Univ Cambridge, Yusuf Hamied Dept Chem, Cambridge, England
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
332-Pos
引用
收藏
页码:67A / 67A
页数:1
相关论文
共 50 条
  • [1] Designer Condensates: A Toolkit for the Biomolecular Architect
    Hastings, Renee L.
    Boeynaems, Steven
    JOURNAL OF MOLECULAR BIOLOGY, 2021, 433 (12)
  • [2] Biomolecular condensates formed by designer minimalistic peptides
    Baruch Leshem, Avigail
    Sloan-Dennison, Sian
    Massarano, Tlalit
    Ben-David, Shavit
    Graham, Duncan
    Faulds, Karen
    Gottlieb, Hugo E.
    Chill, Jordan H.
    Lampel, Ayala
    NATURE COMMUNICATIONS, 2023, 14 (01)
  • [3] Biomolecular condensates formed by designer minimalistic peptides
    Avigail Baruch Leshem
    Sian Sloan-Dennison
    Tlalit Massarano
    Shavit Ben-David
    Duncan Graham
    Karen Faulds
    Hugo E. Gottlieb
    Jordan H. Chill
    Ayala Lampel
    Nature Communications, 14
  • [4] Conformational preferences of disordered proteins in biomolecular condensates
    Wang, Jiahui
    Devarajan, Dinesh Sundaravadivelu
    Kim, Youngchan
    Nikoubashman, Arash
    Mittal, Jeetain
    BIOPHYSICAL JOURNAL, 2024, 123 (03) : 492A - 493A
  • [5] Intrinsically disordered proteins and biomolecular condensates as drug targets
    Biesaga, Mateusz
    Frigole-Vivas, Marta
    Salvatella, Xavier
    CURRENT OPINION IN CHEMICAL BIOLOGY, 2021, 62 : 90 - 100
  • [6] Making the Case for Disordered Proteins and Biomolecular Condensates in Bacteria
    Cohan, Megan C.
    Pappu, Rohit, V
    TRENDS IN BIOCHEMICAL SCIENCES, 2020, 45 (08) : 668 - 680
  • [7] Conformational Freedom and Topological Confinement of Proteins in Biomolecular Condensates
    Scholl, Daniel
    Deniz, Ashok A.
    JOURNAL OF MOLECULAR BIOLOGY, 2022, 434 (01)
  • [8] How Intrinsically Disordered Proteins Modulate Biomolecular Condensates
    Wang, Yanyan
    Chen, Limin
    Li, Siyang
    Lai, Luhua
    PROGRESS IN CHEMISTRY, 2022, 34 (07) : 1610 - 1618
  • [9] Proteins in phase: Unveiling the role of IDPs and structured proteins in biomolecular condensates
    Singh, Arjun
    Dignon, Gregory
    BIOPHYSICAL JOURNAL, 2024, 123 (03) : 72A - 72A
  • [10] Biomolecular condensates: Formation mechanisms, biological functions, and therapeutic targets
    Niu, Xin
    Zhang, Lei
    Wu, Yuchen
    Zong, Zhi
    Wang, Bin
    Liu, Jisheng
    Zhang, Long
    Zhou, Fangfang
    MEDCOMM, 2023, 4 (02):