Trends and Challenges in the Development of 3D-Printed Heart Valves and Other Cardiac Implants: A Review of Current Advances

被引:8
作者
Bhandari, Sagar [1 ]
Yadav, Vikas [2 ]
Ishaq, Aqsa [3 ]
Sanipini, Sailakshmn [4 ]
Ekhator, Chukwuyem [5 ]
Khleif, Rafeef [6 ]
Beheshtaein, Alee [7 ]
Jhajj, Loveleen K. [8 ]
Khan, Aimen Waqar [9 ]
Al Khalifa, Ahmed [10 ]
Naseem, Muhammad Arsal [11 ]
Bellegarde, Sophia B. [12 ]
Nadeem, Muhammad A. [13 ]
机构
[1] Tucson Med Ctr, Cardiol, Tucson, AZ USA
[2] Pt BD Sharma Postgrad Inst Med Sci, Internal Med, Rohtak, Haryana, India
[3] Shaheed Mohtarma Benazir Bhutto Med Univ, Internal Med, Larkana, Pakistan
[4] Xavier Univ, Surg, Sch Med, Oranjestad, Aruba
[5] New York Inst Technol, Coll Osteopath Med, Neurooncol, Old Westbury, NY USA
[6] Xavier Univ, Med, Sch Med, Oranjestad, Aruba
[7] Xavier Univ, Internal Med, Sch Med, Chicago, IL USA
[8] Xavier Univ, Internal Med, Sch Med, Oranjestad, Aruba
[9] Jinnah Sindh Med Univ, Med, Karachi, Pakistan
[10] Sulaiman Alrajhi Univ, Coll Med, Med, Al Bukayriyah, Saudi Arabia
[11] Mayo Hosp, Med, Lahore, Pakistan
[12] Amer Univ Antigua, Pathol & Lab Med, St Johns, Antigua & Barbu
[13] Shifa Int Hosp, Med & Surg, Islamabad, Pakistan
关键词
review; bioprinting; valve; surgery; 3d printing; implant; cardiac; STEM-CELLS; CHITOSAN; FIBRIN;
D O I
10.7759/cureus.43204
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This article provides a comprehensive review of the current trends and challenges in the development of 3D printed heart valves and other cardiac implants. By providing personalized solutions and pushing the limits of regenerative medicine, 3D printing technology has revolutionized the field of cardiac healthcare. The use of several organic and synthetic polymers in 3D printing heart valves is explored in this article, with emphasis on both their benefits and drawbacks. In cardiac tissue engineering, stem cells are essential, and their potential to lessen immunological rejection and thrombogenic consequences is highlighted. In the clinical applications section, the article emphasizes the importance of 3D printing in preoperative planning. Surgery results are enhanced when surgeons can visualize and assess the size and placement of implants using patient-specific anatomical models. Customized implants that are designed to match the anatomy of a particular patient reduce the likelihood of complications and enhance postoperative results. The development of physiologically active cardiac implants, made possible by 3D bioprinting, shows promise by eliminating the need for artificial valves. In conclusion, this paper highlights cutting-edge research and the promise of 3D-printed cardiac implants to improve patient outcomes and revolutionize cardiac treatment.
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页数:9
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