The association between diuretics and falls in older adults: A systematic review and meta-analysis

被引：10
作者：
Bai, Xue [1 ,6 ]
Han, Bing [2 ]
Zhang, Man [3 ]
Liu, Jinfeng [4 ]
Cui, Yi [5 ]
Jiang, Hong [6 ,7 ]
机构：
[1] Fudan Univ, Sch Nursing, Shanghai, Peoples R China
[2] Beijing Ji Shui Tan Hosp, Dept Orthopaed Oncol Surg, Beijing, Peoples R China
[3] Yanan Univ, Sch Med, Yanan 716000, Shaanxi, Peoples R China
[4] Mianyang Cent Hosp, Mianyang City, Sichuan, Peoples R China
[5] Air Force Med Univ, Dept Nursing, Xian, Shaanxi, Peoples R China
[6] Fudan Univ, Huashan Hosp, Shanghai, Peoples R China
[7] Fudan Univ, Huashan Hosp, Dept Neurosurg, 12 Wulumuqi Middle Rd, Shanghai 200433, Peoples R China
来源：
GERIATRIC NURSING | 2023年 / 52卷
关键词：
Older adult; Fall; Diuretic; Meta; -analysis; Systematic review; RISK-INCREASING DRUGS; ANTIHYPERTENSIVE MEDICATIONS; THIAZIDE-DIURETICS; PEOPLE; COMMUNITY; LOOP; POLYPHARMACY; IMPACT;
D O I：
10.1016/j.gerinurse.2023.05.009
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Objective: Diuretic intake increases the risk of falling. However, previous studies have shown inconsistent correlations between diuretics and falls. This meta-analysis aimed to provide a comprehensive overview of the relationship between diuretic use and risk of falls in older adult individuals.Methods: Six databases (Cochrane Library, PubMed, Medline, CINAHL, Web of Science, and EMBASE) were searched from their inception to November 9, 2022. The risk of bias was independently evaluated using the Newcastle-Ottawa Quality Assessment Scale. A comprehensive meta-analysis was used to analyze the eligible studies.Results: Fifteen articles were analyzed. Studies have shown that diuretics can increase the risk of falls in older adult individuals. The probability of falls in older adult individuals who used diuretics was 1.185 times higher than in those who did not take diuretics. Conclusion: Diuretics were significantly associated with an increased risk of falls.& COPY; 2023 Elsevier Inc. All rights reserved.
引用
收藏
页码：106 / 114
页数：9
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