Predictive value of risk factors for prognosis of patients with sepsis in intensive care unit

被引:2
作者
Chen, Caiyu [1 ]
Wu, Xinxin [1 ]
Zhang, Wen [1 ]
Pu, Yuting [1 ]
Xu, Xiangru [1 ]
Sun, Yuting [1 ]
Fei, Yuerong [1 ]
Zhou, Shuang [2 ]
Fang, Bangjiang [1 ,3 ,4 ]
机构
[1] Shanghai Univ Tradit Chinese Med, Longhua Hosp, Dept Emergency, Shanghai, Peoples R China
[2] Shanghai Univ Tradit Chinese Med, Acupuncture & Massage Coll, Shanghai, Peoples R China
[3] Shanghai Univ Tradit Chinese Med, Inst Emergency & Crit Care Med, Shanghai, Peoples R China
[4] Shanghai Univ Tradit Chinese Med, Longhua Hosp, Dept Emergency, Shanghai 200032, Peoples R China
关键词
intensive care unit; predictive value; risk factors; sepsis; SEPTIC SHOCK; MORTALITY; INFECTION; PNEUMONIA;
D O I
10.1097/MD.0000000000033881
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Sepsis has emerged as a major global public health concern due to its elevated mortality and high cost of care. This study aimed to evaluate the risk factors associated with the mortality of sepsis patients in the Intensive Care Unit (ICU), and to intervene in the early stages of sepsis in order to improve patient outcomes and reduce mortality. From January 1st, 2021 to December 31st, 2021, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Huashan Hospital Affiliated to Fudan University, and The Seventh People's Hospital Affiliated to Shanghai University of Traditional Chinese Medicine were designated as sentinel hospitals, and sepsis patients in their respective ICU and Emergency ICU were selected as research subjects, and divided into survivors and non-survivors according to their discharge outcomes. The mortality risk of sepsis patients was subsequently analyzed by logistic regression. A total of 176 patients with sepsis were included, of which 130 (73.9%) were survivors and 46 (26.1%) were non-survivors. Factors identified as having an impact on death among sepsis patients included female [Odds Ratio (OR) = 5.135, 95% confidence interval (CI): 1.709, 15.427, P = .004)], cardiovascular disease (OR = 6.272, 95% CI: 1.828, 21.518, P = .004), cerebrovascular disease (OR = 3.133, 95% CI: 1.093, 8.981, P = .034), pulmonary infections (OR = 6.700, 95% CI: 1.744, 25.748, P = .006), use of vasopressors (OR = 34.085, 95% CI: 10.452, 111.155, P < .001), WBC < 3.5 x 10(9)/L (OR = 9.752, 95% CI: 1.386, 68.620, P = .022), ALT < 7 U/L (OR = 7.672, 95% CI: 1.263, 46.594, P = .027), ALT > 40 U/L (OR = 3.343, 95% CI: 1.097, 10.185, P = .034). Gender, cardiovascular disease, cerebrovascular disease, pulmonary infections, the use of vasopressors, WBC, and ALT are important factors in evaluating the prognostic outcome of sepsis patients in the ICU. This suggests that medical professionals should recognize them expeditiously and implement aggressive treatment tactics to diminish the mortality rate and improve outcomes.
引用
收藏
页数:9
相关论文
共 50 条
  • [1] Epidemiologic features, risk factors, and outcome of sepsis in stroke patients treated on a neurologic intensive care unit
    Berger, Benjamin
    Gumbinger, Christoph
    Steiner, Thorsten
    Sykora, Marek
    JOURNAL OF CRITICAL CARE, 2014, 29 (02) : 241 - 248
  • [2] Risk factors for death in patients with sepsis in an intensive care unit
    do Prado, Patricia Rezende
    Volpati, Natasha Varjao
    Escobar Gimenes, Fernanda Raphael
    Atila, Elisabeth
    Maggi, Luis Eduardo
    Maciel Amaral, Thatiana Lameira
    REV RENE, 2018, 19
  • [3] Diagnostic and predictive performance of biomarkers in patients with sepsis in an intensive care unit
    Zhang, Yu
    Khalid, Sadia
    Jiang, Li
    JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2019, 47 (01) : 44 - 58
  • [4] Risk factors for mortality from sepsis in an intensive care unit in Ecuador A prospective study
    Velez, Jorge W.
    Aragon, Davi C.
    Donadi, Eduardo A.
    Carlotti, Ana P. C. P.
    MEDICINE, 2022, 101 (11)
  • [5] Clinical predictive value of the initial neutrophils to lymphocytes and platelets ratio for prognosis of sepsis patients in the intensive care unit: a retrospective study
    Zhang, Jinhui
    Zhao, Qun
    Hu, Zhenkui
    FRONTIERS IN MEDICINE, 2024, 11
  • [6] Predictive factors for mortality in patients admitted to the intensive care unit
    Ulco Cevallos, Bryan Omar
    Paucar Moromenacho, Johanna Andrea
    Garrido Sanchez, Jhon Jairo
    Llerena Ocana, Fauri Lenin
    Molina Espinosa, Maria Paulina
    Perez Naranjo, Mauricio Enrique
    Cadena Cevallos, Juan Daniel
    Ponce Romerate, Juan Carlos
    Parco Cuje, Pamela Gissel
    REVISTA LATINOAMERICANA DE HIPERTENSION, 2023, 18 (06): : 261 - 265
  • [7] Thrombocytopenia: A Risk Factor of Mortality for Patients with Sepsis in the Intensive Care Unit
    Burunsuzoglu, Bunyamin
    Salturk, Cuneyt
    Karakurt, Zuhal
    Ongel, Esra Akkutuk
    Takir, Huriye Berk
    Kargin, Feyza
    Horzum, Gulbanu
    Balci, Merih
    Mocin, Ozlem
    Adiguzel, Nalan
    Gungor, Gokay
    Yilmaz, Adnan
    TURKISH THORACIC JOURNAL, 2016, 17 (01): : 7 - 14
  • [8] Validity of presepsin for the diagnosis and prognosis of sepsis in elderly patients admitted to the Intensive Care Unit
    Wang, Shuang
    Ruan, Wen-Qing
    Yu, Zhuang
    Zhao, Xiang
    Chen, Zhi-Xia
    Li, Quan
    MINERVA ANESTESIOLOGICA, 2020, 86 (11) : 1170 - 1179
  • [9] Systemic inflammatory response index improves prognostic predictive value in intensive care unit patients with sepsis
    Xu, Tuo
    Song, Shuaiwei
    Zhu, Ke
    Yang, Yin
    Wu, Chengyu
    Wang, Naixue
    Lu, Shu
    SCIENTIFIC REPORTS, 2025, 15 (01):
  • [10] A systematic review on risk factors associated with sepsis in patients admitted to intensive care units
    Fathi, Mohammad
    Markazi-Moghaddam, Nader
    Ramezankhani, Azra
    AUSTRALIAN CRITICAL CARE, 2019, 32 (02) : 155 - 164