Anti-Markovnikov Hydrogermylation of Alkenes via Lewis Acid Catalysis

被引：11

作者：

Selmani, Aymane ^{[1
]}

Schoenebeck, Franziska ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, Landoltweg 1, D-52074 Aachen, Germany

来源：

SYNTHESIS-STUTTGART | 2023年 / 55卷 / 11期

基金：

欧洲研究理事会;

关键词：

organogermanes; hydrogermylation; Lewis acid; catalysis; anti-Markovnikov; C-H FUNCTIONALIZATION; BIARYL SYNTHESIS; ACCESS;

D O I：

10.1055/a-2036-3868

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The direct hydrogermylation of alkenes under Lewis acid catalysis is reported. The use of borane B(C6F5)3 as a catalyst allows for a mild, metal-free hydrogermylation of alkenes and concomitant reduction of ketones and aldehydes. Regardless of electronic biases, anti-Markovnikov hydrogermylation is observed in high yields. Moreover, the process is scalable and proceeds under mild conditions at room temperature.

引用

页码：1792 / 1798

页数：7

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