Current Management of Stage IIIA (N2) Non-Small-Cell Lung Cancer Role of Perioperative Immunotherapy, and Tyrosine Kinase Inhibitors

被引:1
作者
Bryan, Darren S. [1 ]
Donington, Jessica S. [1 ]
机构
[1] Univ Chicago Med, Dept Surg, Sect Thorac Surg, Room S-546 MC 5047,5841 South Maryland Ave, Chicago, IL 60637 USA
关键词
Non-small-cell lung cancer; Multimodality therapy; Surgery; Stage III; Induction therapy; Immunotherapy; NEOADJUVANT THERAPY; SURGICAL RESECTION; PLUS CHEMOTHERAPY; ADJUVANT THERAPY; NIVOLUMAB; PHASE-3; PEMBROLIZUMAB; RADIOTHERAPY; OSIMERTINIB; MUTATIONS;
D O I
10.1016/j.thorsurg.2023.01.006
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
There have been numerous recent advances in the treatmetn of stage IIIA non-small cell lung cancer. The most significant involve the addition of targeted therapies adn immune checkpoint inhibitors into perioperative care. These exciting advances are improving survival in this challenging patient population, but some-decade old controveries around the definition of resectability, prognositic importance of tumor response to induction therapy, and the role of pneumonectomy persist. Copyright © 2023 Elsevier Inc. All rights reserved.
引用
收藏
页码:189 / 196
页数:8
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