Divergent upgrading pathways of sulfones with primary alcohols: nickel-catalyzed α-alkylation under N2 and metal-free promoted β-olefination in open air

被引：6

作者：

Yu, Haiping ^{[1
]}

Fu, Kaiyue ^{[1
]}

Yang, Guang ^{[1
]}

Liu, Mengyu ^{[1
]}

Yang, Peng ^{[1
,2
]}

Liu, Tao ^{[1
]}

机构：

[1] Shandong Normal Univ, Coll Chem, Chem Engn & Mat Sci, Jinan 250014, Peoples R China

[2] Taiyuan Univ Technol, State Key Lab Clean & Efficient Coal Utilizat, Taiyuan 030024, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 05期

基金：

中国国家自然科学基金;

关键词：

BORROWING HYDROGEN; UNACTIVATED AMIDES; C-ALKYLATION; KETONES; ESTERS; NITRILES; ACTIVATION; CHEMISTRY; SECONDARY; PHENYL;

D O I：

10.1039/d2cc05882k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report here our findings on the diverse reaction results of sulfones and alcohols. In the presence of NiCl2/P(t-Bu)(3) and under a N-2 atmosphere, alpha-C-alkylation of sulfones with alcohols occurs through a borrowing-hydrogen mechanism; when the reaction was carried out in the open air without nickel, the product was not the predicted alpha,beta-unsaturated sulfone, but the beta-alkenyl sulfone, which is a useful building block in organic synthesis.

引用

页码：615 / 618

页数：4

共 49 条

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