Two new alkaloids isolated from Dictamnus dasycarpus Turcz

被引：0

作者：

Ye, Sun ^{[1
]}

Liu, Yan ^{[1
]}

Wang, Si-Yi ^{[1
]}

Guo, Ming-Yuan ^{[1
]}

Wu, Jia-Tong ^{[1
]}

Hao, Zhi-Chao ^{[1
]}

Pan, Juan ^{[1
]}

Guan, Wei ^{[1
]}

Kuang, Hai-Xue ^{[1
]}

Yang, Bing-You ^{[1
]}

机构：

[1] Heilongjiang Univ Chinese Med, Key Lab Basic & Applicat Res Beiyao, Minist Educ, Harbin, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2024年

关键词：

Dictamnus dasycarpus Turcz; quinoline alkaloids; anti-proliferation; QUINOLINE ALKALOIDS; CONSTITUENTS; LIMONOIDS;

D O I：

10.1080/14786419.2024.2305207

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two new quinoline alkaloids (1-2) together with twenty-two known alkaloids (3-24) were isolated and identified from Dictamnus dasycarpus Turcz. Compounds 6-7, 9, 11, 15-16, 19 and 24 were isolated from D. dasycarpus for the first time. The structures of all compounds were characterised by spectroscopic methods (1D, 2D NMR and HRESIMS). The anti-proliferative activity was mediated by the arrest of three human cancer cell lines (SW982, HepG2 and A549) of all the compounds that were evaluated by CCK-8 assay. [GRAPHICS]

引用

页数：8

共 28 条

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