Morphogenesis in space offers challenges and opportunities for soft matter and biophysics

被引:2
作者
Ben Amar, Martine [1 ,2 ]
Ciarletta, Pasquale [3 ]
Haas, Pierre A. [4 ,5 ,6 ]
机构
[1] Univ Paris Cite, Univ PSL, Sorbonne Univ, Lab Phys,Ecole Normale Super,CNRS, 24 Rue Lhomond, F-75005 Paris, France
[2] Sorbonne Univ, Inst Univ Cancerol, Fac Med, 91 Blvd Hop, F-75013 Paris, France
[3] Politecn Milan, Dipartimento Matemat, MOX Lab, I-20133 Milan, Italy
[4] Max Planck Inst Phys Komplexer Syst, Nothnitzer Str 38, D-01187 Dresden, Germany
[5] Max Planck Inst Mol Cell Biol & Genet, Pfotenhauerstr 108, D-01307 Dresden, Germany
[6] Ctr Syst Biol Dresden, Pfotenhauerstr 108, D-01307 Dresden, Germany
关键词
ROTATING-WALL VESSEL; RAYLEIGH-TAYLOR INSTABILITY; POTENTIAL FLOW-ANALYSIS; PLURIPOTENT STEM-CELLS; SIMULATED MICROGRAVITY; MECHANICAL FEEDBACK; PATTERN-FORMATION; GROWING TISSUES; GENE-EXPRESSION; HUMAN LIVER;
D O I
10.1038/s42005-023-01242-9
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
The effects of microgravity on soft matter morphogenesis have been documented in countless experiments, but physical understanding is still lacking in many cases. Here we review how gravity affects shape emergence and pattern formation for both inert matter and living systems of different biological complexities. We highlight the importance of building physical models for understanding the experimental results available. Answering these fundamental questions will not only solve basic scientific problems, but will also enable several industrial applications relevant to space exploration.
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页数:10
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