On a singular limit as ?? 0 for a model for the evolution of morphogens in a growing tissue

被引:0
作者
Coclite, G. M. [1 ]
Coclite, M. [2 ]
机构
[1] Politecn Bari, Dipartimento Meccan Matemat & Management, Via E Orabona 4, I-70125 Bari, Italy
[2] Univ Bari, Dipartimento Matemat, Via E Orabona 4, I-70125 Bari, Italy
来源
ZEITSCHRIFT FUR ANGEWANDTE MATHEMATIK UND PHYSIK | 2023年 / 74卷 / 03期
关键词
Singular diffusion; Neumann boundary conditions; Singular limit; Morphogen evolution; PATTERN; GROWTH;
D O I
10.1007/s00033-023-01993-z
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
This paper is devoted to the singular limit of a model for the regulation of growth and patterning in developing tissues by diffusing morphogens. The model is governed by a system of nonlinear PDEs. The arguments are based on energy estimates and a change of variable that reduces the system into a nonlinear PDE with singular diffusion.
引用
收藏
页数:23
相关论文
共 12 条
[1]   The Decapentaplegic morphogen gradient: from pattern formation to growth regulation [J].
Affolter, Markus ;
Basler, Konrad .
NATURE REVIEWS GENETICS, 2007, 8 (09) :663-674
[2]   Scaling morphogen gradients during tissue growth by a cell division rule [J].
Averbukh, Inna ;
Ben-Zvi, Danny ;
Mishra, Siddhartha ;
Barkai, Naama .
DEVELOPMENT, 2014, 141 (10) :2150-2156
[3]   Long time behavior of a model for the evolution of morphogens in a growing tissue [J].
Coclite, G. M. ;
Coclite, M. M. .
PARTIAL DIFFERENTIAL EQUATIONS AND APPLICATIONS, 2020, 1 (01)
[4]   Long time behavior of a model for the evolution of morphogens in a growing tissue II: θ < log 2 [J].
Coclite, G. M. ;
Coclite, M. M. .
JOURNAL OF DIFFERENTIAL EQUATIONS, 2021, 272 :1015-1049
[5]  
Coclite GM, 2017, Z ANGEW MATH PHYS, V68, DOI 10.1007/s00033-017-0838-0
[6]   On a model for the evolution of morphogens in growing tissue III: θ < log(2) [J].
Coclite, G. M. ;
Coclite, M. M. .
JOURNAL OF DIFFERENTIAL EQUATIONS, 2017, 263 (02) :1079-1124
[7]   ON A MODEL FOR THE EVOLUTION OF MORPHOGENS IN A GROWING TISSUE [J].
Coclite, G. M. ;
Coclite, M. M. ;
Mishra, S. .
SIAM JOURNAL ON MATHEMATICAL ANALYSIS, 2016, 48 (03) :1575-1615
[8]   THEORY OF BIOLOGICAL PATTERN FORMATION [J].
GIERER, A ;
MEINHARDT, H .
KYBERNETIK, 1972, 12 (01) :30-39
[9]   Regulation of Organ Growth by Morphogen Gradients [J].
Schwank, Gerald ;
Basler, Konrad .
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2010, 2 (01) :a001669
[10]   Dynamics of Dpp Signaling and Proliferation Control [J].
Wartlick, O. ;
Mumcu, P. ;
Kicheva, A. ;
Bittig, T. ;
Seum, C. ;
Juelicher, F. ;
Gonzalez-Gaitan, M. .
SCIENCE, 2011, 331 (6021) :1154-1159