Clinical profile of patients with cardiac amyloidosis in India

被引:5
作者
Mohan, Bishav [1 ]
Singh, Suvir [2 ,5 ]
Tandon, Rohit [1 ]
Batta, Akash [1 ]
Singal, Gautam [1 ]
Singh, Gurbhej [1 ]
Singh, Bhupinder [1 ,3 ]
Goyal, Abhishek [1 ]
Chhabra, Shibba Takkar [1 ]
Naved, Khizar [4 ]
Jain, Aayush [2 ]
Wander, Gurpreet S. [1 ]
机构
[1] Dayanand Med Coll & Hosp, Hero DMC Heart Inst, Unit, Ludhiana, India
[2] Dayanand Med Coll & Hosp, Ludhiana, India
[3] AIIMS, Bathinda, India
[4] Kasturba Med Coll & Hosp, Manipal, India
[5] Dayanand Med Coll & Hosp, Dept Clin Haematol & Stem Cell Transplantat, Ludhiana, India
关键词
Amyloid; Cardiac; Myeloma; TTR; Cancer; PRIMARY SYSTEMIC AMYLOIDOSIS;
D O I
10.1016/j.ihj.2022.12.006
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Limited data exists on patients with cardiac amyloidosis (CA) in India, due to underdiagnosis and late presentation. We present single centre data from 13 patients over a 4 year period with a median age of 65 years. A majority presented with symptomatic heart failure (69%) and eight patients had confirmed AL amyloidosis. At the end of the follow up period, 46% patients died, with 30% of the overall cohort dead within six months. Among the survivors, 71% continue to have NYHA grade III/IV symptoms. A suggested algorithm for earlier diagnosis in resource constrained settings is also presented.(c) 2022 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
引用
收藏
页码:73 / 76
页数:4
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