Early versus delayed amniotomy with immediate oxytocin after Foley catheter cervical ripening in multiparous women with labor induction: A randomized controlled trial

被引:6
作者
Jamaluddin, Arifah [1 ]
Azhary, Jerilee Mariam Khong [1 ]
Hong, Jesrine Gek Shan [1 ]
Hamdan, Mukhri [1 ]
Tan, Peng Chiong [1 ]
机构
[1] Univ Malaya, Fac Med, Dept Obstet & Gynecol, Jalan Prof Diraja Ungku Aziz, Kuala Lumpur 50603, Malaysia
关键词
cesarean; delayed amniotomy; early amniotomy; Foley catheter; labor induction; maternal satisfaction; multipara; oxytocin; oxytocin-to-delivery interval; PAROUS WOMEN; AUGMENTATION;
D O I
10.1002/ijgo.14361
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective To evaluate immediate oxytocin and early amniotomy compared with delayed amniotomy after Foley catheter cervical ripening in multiparous women on intervention-to-delivery interval. Methods This randomized trial was conducted in Malaysia in 232 term multiparous women with balloon catheter-ripened cervixes (dilatation >= 3 cm), singleton fetus, cephalic presentation with intact membranes, and reassuring fetal heart rate tracing. They were randomized to immediate titrated intravenous oxytocin infusion and early amniotomy (116) or delayed amniotomy after 4 h of oxytocin (116). Primary outcome was intervention (oxytocin initiation)-to-delivery interval. Results Oxytocin-to-delivery intervals were a median of 4.99 h (interquartile range [IQR], 3.21-7.82 h) versus 6.23 h (IQR, 4.50-8.45 h) (P < 0.001) for the early versus delayed amniotomy arms, respectively. Delivery rate at 4 h and 6 h after oxytocin infusion were 40 of 116 (35%) versus 22 of 116 (19%) (relative risk [RR], 1.82 [95% confidence interval (CI), 1.16-2.86], P = 0.011) and 77 of 116 (66%) versus 54 of 116 (47%) (RR, 1.43 [95% CI, 1.13-1.80], P = 0.003) for the early versus delayed amniotomy arms, respectively. Maternal satisfaction on birth process were 7 (IQR, 6-8) versus 7 (IQR, 7-8) (P = 0.006), uterine hyperstimulation rates were 10 of 116 (9%) versus 14 of 116 (12%) (RR, 0.71 [95% CI, 0.33-1.54]) (P = 0.519), and Cesarean delivery rates were 17 of 116 (15%) versus 19 of 116 (16%) (RR, 0.90 [95% CI, 0.49-1.63], P = 0.856) for the early versus delayed amniotomy arms, respectively. Conclusion In multiparas at term following cervical ripening by Foley catheter, immediate oxytocin and early amniotomy compared with a scheduled 4-h delay to amniotomy shortens the interval to birth and decreases uterine hyperactivity in labor but lowers maternal satisfaction. The cesarean delivery rate is not significantly reduced. Clinical Trial Registration This study was registered with the International Standard Randomised Controlled Trial Number (ISRCTN) on September 29, 2020, with trial identification number: ISRCTN87066007 (). The first participant was recruited on September 29, 2020, after ISRCTN registry confirmation was received.
引用
收藏
页码:661 / 669
页数:9
相关论文
共 25 条
  • [1] Which method is best for the induction of labour? A systematic review, network meta-analysis and cost-effectiveness analysis
    不详
    [J]. HEALTH TECHNOLOGY ASSESSMENT, 2016, 20 (65) : 1 - +
  • [2] [Anonymous], 2007, INTR CAR CAR HLTH WO
  • [3] [Anonymous], 2009, OBSTET GYNECOL, V114, P386, DOI [DOI 10.1097/AOG.0B013-3181B48EF5, DOI 10.1097/AOG.0B013E3181B48EF5, 10.1097/AOG.0b013e3181b48ef5]
  • [4] First do no harm - interventions during labor and maternal satisfaction: a descriptive cross-sectional study
    Calik, Kiymet Yesilcicek
    Karabulutlu, Ozlem
    Yavuz, Canan
    [J]. BMC PREGNANCY AND CHILDBIRTH, 2018, 18
  • [5] Searches for supersymmetry at the Large Hadron Collider
    Canepa A.
    [J]. Reviews in Physics, 2019, 4
  • [6] Early amniotomy after cervical ripening for induction of labor: a systematic review and meta-analysis of randomized controlled trials
    De Vivo, Valentino
    Carbone, Luigi
    Saccone, Gabriele
    Magoga, Giulia
    De Vivo, Generoso
    Locci, Mariavittoria
    Zullo, Fulvio
    Berghella, Vincenzo
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2020, 222 (04) : 320 - 329
  • [7] Early versus late amniotomy for labour induction: a randomized controlled trial
    Gagnon-Gervais, Karine
    Bujold, Emmanuel
    Iglesias, Marie-Helene
    Duperron, Louise
    Masse, Andre
    Mayrand, Marie-Helene
    Sansregret, Andree
    Fraser, William
    Audibert, Francois
    [J]. JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 2012, 25 (11) : 2326 - 2329
  • [8] Early amniotomy increases the frequency of fetal heart rate abnormalities
    Goffinet, F
    Fraser, W
    Marcoux, S
    Breart, G
    Moutquin, JM
    Daris, M
    Armson, BA
    PhalenKelly, K
    Verrault, JP
    Paradis, G
    Poulin, G
    Moreau, L
    Okun, N
    Nimrod, C
    Villeneuve, M
    Joshi, AK
    Nault, C
    Cohen, H
    Weston, J
    Doran, T
    Jordan, A
    Bernstein, P
    Carroll, J
    Pierce, C
    Bayer, L
    Kang, A
    Bottoms, S
    Norman, G
    Galerneau, F
    Jansen, P
    [J]. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1997, 104 (05): : 548 - 553
  • [9] Outpatient versus inpatient Foley catheter induction of labor in multiparas with unripe cervixes: A randomized trial
    Hamdan, Mukhri
    Shuhaina, Shuib
    Hong, Jesrine Gek Shan
    Vallikkannu, Narayanan
    Zaidi, Syeda Nureena
    Tan, Yi Pin
    Tan, Peng Chiong
    [J]. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2021, 100 (11) : 1977 - 1985
  • [10] Comparison of Labor progression between induced and noninduced multiparous women
    Hoffman, Matthew K.
    Vahratian, Anjel
    Sciscione, Anthony C.
    Troendle, James F.
    Zhang, Jun
    [J]. OBSTETRICS AND GYNECOLOGY, 2006, 107 (05) : 1029 - 1034