Non-alcoholic fatty liver disease: Definition and subtypes

被引:123
作者
Han, Seul Ki [1 ,2 ,3 ]
Baik, Soon Koo [1 ,2 ,3 ]
Kim, Moon Young [1 ,2 ,3 ]
机构
[1] Yonsei Univ, Dept Internal Med, Wonju Coll Med, Wonju, South Korea
[2] Yonsei Univ, Regenerat Med Res Ctr, Wonju Coll Med, Wonju, South Korea
[3] Yonsei Univ, Cell Therapy & Tissue Engn Ctr, Wonju Coll Med, Wonju, South Korea
关键词
Non-alcoholic fatty liver disease; Steatohepatitis; Fibrosis; METABOLICALLY HEALTHY OBESITY; CRYPTOGENIC CIRRHOSIS; RISK-FACTORS; FIBROSIS PROGRESSION; NATURAL-HISTORY; HEPATOCELLULAR-CARCINOMA; HISTOLOGIC FEATURES; STEATOHEPATITIS; ASSOCIATION; PREVALENCE;
D O I
10.3350/cmh.2022.0424
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide, with a global prevalence of approximately 30%. However, the prevalence of NAFLD has been variously reported depending on the comorbidities. The rising prevalence of obesity in both the adult and pediatric populations is projected to consequently continue increasing NAFLD prevalence. It is a major cause of chronic liver disease worldwide, including cirrhosis and hepatocellular carcinoma (HCC). NAFLD has a variety of clinical phenotypes and heterogeneity due to the complexity of pathogenesis and clinical conditions of its occurrence, resulting in various clinical prognoses. In this article, we briefly described the basic definition of NAFLD and classified the subtypes based on current knowledge in this field.
引用
收藏
页码:S5 / S16
页数:12
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