Effectiveness of a Novel Compound HAIR & SCALP COMPLEX on Hair Follicle Regeneration

被引:2
|
作者
Ferruggia, Greta [1 ]
Contino, Martina [1 ]
Zimbone, Massimo [2 ]
Brundo, Maria Violetta [1 ]
机构
[1] Univ Catania, Dept Biol Geol & Environm Sci, Via Androne 81, I-95124 Catania, Italy
[2] Natl Res Council Italy CNR IMM, Inst Microelect & Microsyst, I-95123 Catania, Italy
关键词
exosomes; growth factors; cytokines; hair growth; GROWTH; COMPONENTS; EXOSOMES; ALOPECIA; MILK;
D O I
10.3390/cosmetics11010010
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Background: People lose between 50 and 100 hairs a day and generate new ones from stem cells in hair follicles, but in those suffering from baldness, the stem cells remain inactive and are unable to regenerate new hair. Although 9% of hair follicles remain in telogen at any time, a variety of factors, including growth factors and cytokines, promote the transition from telogen to anagen and the subsequent stimulation of hair growth. Methods: We compared in vitro, on cultures of human hair follicles, the effect on hair growth and regeneration of the dermal papilla of plant-derived nanovesicles, exosomes from cord blood stem cells and bovine colostrum, a mixture of growth factors and cytokines purified from bovine colostrum, called GF20, and a new compound called HAIR & SCALP COMPLEX obtained by adding exosomes isolated from colostrum to GF20. Results: The analyses demonstrated a significant increase in the growth of the bulb and the regeneration of the dermal papilla in the samples treated with HAIR & SCALP COMPLEX compared to the other elements tested. Conclusions: In this research, we propose a possible new treatment that could help significantly slow down hair loss and encourage new hair growth: HAIR & SCALP COMPLEX.
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页数:13
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