Heart heart failure with preserved ejection fraction-Update 2022 br

被引：0

作者：

Gerges, M. ^{[1
]}

Bonderman, D. ^{[1
,2
]}

机构：

[1] Wiener Gesundheitsverbund, 5 Med Abt mit Kardiol, Klin Favoriten, Vienna, Austria

[2] Wiener Gesundheitsverbund, Med Abt mit Kardiol 5, Klin Favoriten, Kundratstr 3, A-1100 Vienna, Austria

来源：

JOURNAL FUR KARDIOLOGIE | 2023年 / 30卷 / 1-2期

关键词：

heart failure with preserved ejection fraction (HFpEF); sodium-glucose cotransporter 2 inhibitor (SGLT2-i); angiotensin receptor neprilysin inhibitor (ARNI); 20-YEAR TRENDS; EPIDEMIOLOGY; HOSPITALIZATION; PREVALENCE; OUTCOMES; DIAGNOSIS; SURVIVAL; SEX; RECOMMENDATIONS; SPIRONOLACTONE;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart heart failure with preserved ejection fraction - Update 2022.. Until now no treatment had convincingly shown a reduction in mortality and morbidity in heart failure with preserved ejection fraction (HFpEF). The EMPEROR -Preserved trial, empagliflozin in HFpEF, is the first positive outcome study that reduced the combined risk for cardiovascular death or hospitalization, whether suffering from type 2 diabetes or not [1]. The DELIVER study, dapagliflozin in HFpEF, significantly reduced the primary endpoint of cardiovascular death or worsening in heart failure with mildly reduced ejection fraction (HFmrEF) or HFpEF [2, 3]. Current ESC guidelines further recommend the use of sacubitril/valsar tan and spironolactone in HFmrEF patients. Supporting data were provided by a sub-group analysis of the PARAGON-HF study showing a reduction in HF-related hospitalizations and a meta-analysis of the PARADIGM-HF and PARAGON-HF studies showing a reduction in cardiovascular deaths and HF-related hospitalizations

引用

页码：18 / 23

页数：8

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