Objective: This study aims to adapt the Patient-Nurse Trust Scale to Turkish and perform validity and reliability analyses. Methods: This study has been conducted as methodological. It was conducted between February 2021 and June 2021 in a training and research hospital in Istanbul, Turkey. The study was completed with 311 participants. Introductory Information Form, Patient-Nurse Trust Scale, and Trust in Nurses Scale were used for data collection. In addition to descriptive statistics, language validity, content validity, construct validity, criterion-related validity, discrimination, internal consistency reliability, two-half test reliability, and item analysis methods were used to determine the scale's psychometric properties. Results: As a result of factor analysis, it was determined that the scale showed a single factor structure, and explained 66.63% of the total variance. Item factor load values were found to vary between .74 and .88. The ratio of the chi-square value to the degrees of freedom (397.496/112) was found to be 3.549. It was found that RMSEA=.09, GFI=.86, IFI=.93, NFI=.91, CFI=.93, and RFI=.87. It was found that the correlations of all items varied between .71 and .87. The Chronbach's alpha value for the whole scale was calculated as .97. As a result of parallel test analysis, it was determined that there was a significant positive correlation between both scales (r=.301; p=.000). Conclusion: The exploratory factor analysis and confirmatory factor analysis results of the Turkish version of the scale are acceptable, and their reliability indexes are high.