Genetic causes and cardiovascular consequences of clonal hematopoiesis in the UK Biobank

被引:0
作者
Beeler, J. Scott [1 ]
Bick, Alexander G. [2 ]
Bolton, Kelly L. [3 ]
机构
[1] Washington Univ, Sch Med, Dept Med, St Louis, MO USA
[2] Vanderbilt Univ, Med Ctr, Dept Med, Div Genet Med, Nashville, TN USA
[3] Washington Univ, Sch Med, Div Oncol, Dept Med, St Louis, MO 63110 USA
来源
NATURE CARDIOVASCULAR RESEARCH | 2023年 / 2卷 / 01期
关键词
RISK;
D O I
10.1038/s44161-022-00198-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pioneering cohort studies including the Framingham Heart Study have led to major insights into cardiovascular disease. However, these studies are underpowered to identify the effects of less common risk factors on human health. This has motivated the development of the UK Biobank, a biomedical database linking health and genetic information in 500,000 individuals.
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页码:13 / 15
页数:3
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