Preliminary Assessment of Safety and Tolerability of Avacopan During the Early Access Program for ANC A-Associated Vasculitis

被引:5
作者
van Leeuwen, Jolijn R. [1 ]
Popov, Tamara [2 ]
Obergfell, Achim [2 ]
Rabelink, Ton J. [1 ]
Teng, Y. K. Onno [1 ,3 ]
机构
[1] Leiden Univ, Med Ctr, Ctr Expertise Lupus Vasculitis & Complement Mediat, Dept Internal Med,Nephrol Sect, Leiden, Netherlands
[2] Vifor Pharm Ltd, Glattbrugg, Switzerland
[3] Leiden Univ Med Ctr LUMC, Dept Nephrol, POB 9600, NL-2300 RC Leiden, Netherlands
关键词
D O I
10.2147/BTT.S394843
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页码:11 / 14
页数:4
相关论文
共 7 条
[1]   Avacopan as First-Line Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Steroid-Sparing Option [J].
Gabilan, Charlotte ;
Pfirmann, Pierre ;
Ribes, David ;
Rigothier, Claire ;
Chauveau, Dominique ;
Casemayou, Audrey ;
Huart, Antoine ;
Schanstra, Joost ;
Colombat, Magali ;
Faguer, Stanislas ;
Belliere, Julie .
KIDNEY INTERNATIONAL REPORTS, 2022, 7 (07) :1115-1118
[2]   Avacopan for the Treatment of ANCA-Associated Vasculitis [J].
Jayne, David R. W. ;
Merkel, Peter A. ;
Schall, Thomas J. ;
Bekker, Pirow .
NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (07) :599-609
[3]   Randomized Trial of C5a Receptor Inhibitor Avacopan in ANCA-Associated Vasculitis [J].
Jayne, David R. W. ;
Bruchfeld, Annette N. ;
Harper, Lorraine ;
Schaier, Matthias ;
Venning, Michael C. ;
Hamilton, Patrick ;
Burst, Volker ;
Grundmann, Franziska ;
Jadoul, Michel ;
Szombati, Istvan ;
Tesar, Vladimir ;
Segelmark, Marten ;
Potarca, Antonia ;
Schall, Thomas J. ;
Bekker, Pirow .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2017, 28 (09) :2756-2767
[4]   Adjunctive Treatment With Avacopan, an Oral C5a Receptor Inhibitor, in Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis [J].
Merkel, Peter A. ;
Niles, John ;
Jimenez, Richard ;
Spiera, Robert F. ;
Rovin, Brad H. ;
Bomback, Andrew ;
Pagnoux, Christian ;
Potarca, Antonia ;
Schall, Thomas J. ;
Bekker, Pirow .
ACR OPEN RHEUMATOLOGY, 2020, 2 (11) :662-671
[5]   Compassionate Use of Avacopan in Difficult-to-Treat Antineutrophil Cytoplasmic Antibody-Associated Vasculitis [J].
van Leeuwen, Jolijn R. ;
Bredewold, Obbo W. ;
van Dam, Laura S. ;
Werkman, Stella L. ;
Jonker, Jacqueline T. ;
Geelhoed, Miranda ;
Langeveld, Antonius P. M. ;
Remmelts, Hilde H. F. ;
van den Broecke, Maud M. ;
Ray, Argho ;
Rabelink, Ton J. ;
Teng, Y. K. Onno .
KIDNEY INTERNATIONAL REPORTS, 2022, 7 (03) :624-628
[6]  
Vifor Pharma press releases, 2022, VFMCRP RECEIVES EU A
[7]   ANCA-associated vasculitis [J].
Yates, Max ;
Watts, Richard .
CLINICAL MEDICINE, 2017, 17 (01) :60-64