COVID-19 and Chronic Kidney Disease: A Narrative Review

被引：4

作者：

Martins, Marilia Paiva ^{[1
]}

de Oliveira, Rodrigo Bueno ^{[1
,2
,3
]}

机构：

[1] Univ Campinas UNICAMP, Sch Med Sci, BR-13083970 Campinas, SP, Brazil

[2] Univ Campinas UNICAMP, Sch Med Sci, Dept Internal Med, Div Nephrol, BR-13083970 Campinas, SP, Brazil

[3] Univ Estadual Campinas, Sch Med Sci, Div Nephrol, Rua Tessalia Vieira de Camargo 126,Cidade Univ Zef, BR-13083887 Campinas, SP, Brazil

来源：

COVID | 2023年 / 3卷 / 08期

关键词：

COVID-19; SARS-CoV-2; chronic kidney disease; dialysis; kidney transplant; CLINICAL CHARACTERISTICS; HEMODIALYSIS-PATIENTS; HOSPITALIZED-PATIENTS; OUTCOMES; INJURY; INFECTION; TRANSPLANTATION; DIALYSIS; UREMIA; VACCINATION;

D O I：

10.3390/covid3080080

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The coronavirus disease-2019 (COVID-19) pandemic has had a profound impact on the world, causing loss of life, economic damage, and social disruption. Individuals with chronic kidney disease (CKD) are prone to complications and increased mortality related to COVID-19. Efforts have been made to increase understanding of the effects of COVID-19 in individuals with CKD. This paper aims to gather and discuss the state-of-the-art in the COVID-19 and CKD literature, involving the early history of COVID-19, the immunological aspects of CKD (such as abnormalities in neutrophilicand dendritic cells functions), the mechanisms of kidney injury by SARS-CoV-2 (for example, viral tropism to kidney tissue and direct cytotoxicity), the clinical course of the disease and consequences for CKD individuals (including kidney transplant recipients), and the emerging treatments (such as the use of Remdesivir, nirmatrelvir, and monoclonal neutralizing antibodies) and immunization for the CKD population.

引用

页码：1092 / 1105

页数：14

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