Visible light triggered synthesis of spiro[indoline-3,4'-quinoline] via oxidative coupling of indole with enaminone and malononitrile

被引：7

作者：

Maury, Suresh Kumar ^{[1
]}

Kushwaha, Ambuj Kumar ^{[1
]}

Kamal, Arsala ^{[1
]}

Singh, Himanshu Kumar ^{[1
]}

Singh, Sundaram ^{[1
]}

机构：

[1] Indian Inst Technol BHU, Dept Chem, Varanasi 221005, UP, India

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2023年 / 1274卷

关键词：

Multicomponent synthesis; Visible-light initiated; Spiro[indoline-3; 4?-quinoline; Oxidative coupling; Enaminone; ONE-POT SYNTHESIS; MULTICOMPONENT REACTIONS; CATALYZED SYNTHESIS; DERIVATIVES; DESIGN;

D O I：

10.1016/j.molstruc.2022.134452

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

In the most recent research, a straightforward, effective, and environmentally friendly method for pro-ducing spiro[indoline-3,4'-quinoline] was developed in ethanol using a photocatalyst eosin y and a 22 W LED lamp. This method involves the oxidative coupling of indole with enaminone and malononitrile. This method's key features include the absence of metals, low cost, environmental friendliness, greenness, non-toxicity, ease of handling, and use of renewable energy like visible light. This method exhibits a wide substrate scope for indole and active methylene compounds, including different enaminones. For the first time, spiro compounds were produced using visible light-mediated metal-free multicomponent synthesis under benign reaction conditions.(c) 2022 Elsevier B.V. All rights reserved.

引用

页数：8

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