Nickel-catalyzed cross-electrophile coupling of unactivated (hetero)aryl sulfone with aryl bromide

被引：17

作者：

Li, Wen-Xin ^{[1
]}

Huo, Bo-Jie ^{[1
]}

Huang, Jie-Ying ^{[1
]}

Rao, Weidong ^{[3
]}

Xu, Hao ^{[1
]}

Zhou, Xiaocong ^{[1
,2
]}

Shen, Zhi-Liang ^{[1
]}

机构：

[1] Nanjing Tech Univ, Tech Inst Fluorochem TIF, Inst Adv Synth, Sch Chem & Mol Engn, Nanjing 211816, Peoples R China

[2] Jiaxing Univ, Coll Biol Chem Sci & Engn, 118 Jiahang Rd, Jiaxing 314001, Peoples R China

[3] Nanjing Forestry Univ, Coll Chem Engn, Jiangsu Prov Key Lab Chem & Utilizat Agroforest Bi, Nanjing 210037, Peoples R China

来源：

JOURNAL OF CATALYSIS | 2024年 / 430卷

基金：

中国国家自然科学基金;

关键词：

Desulfonylation; Cross; -coupling; Aryl sulfone; Nickel; Magnesium; Biaryl; DIRECT INSERTION; ALKYL-HALIDES; ACTIVATION; FUNCTIONALIZATION; REAGENTS; IODIDES; SULFUR; SALTS;

D O I：

10.1016/j.jcat.2024.115359

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A nickel-catalyzed cross-electrophile coupling of unactivated (hetero)aryl sulfones with aryl bromides via C-S bond activation at ambient temperature is developed. By relying on the use of nickel as catalyst, 2,2 '-bipyridine (bpy) as ligand, magnesium turnings as mediator, and THF as solvent, a myriad of biaryls could be facilely prepared in moderate to good yields with reasonable functionality compatibility. The present method potentially serves as an attractive alternative to conventional methods, for the use of unreadily available, relatively expensive, and sensitive organometallic reagents could be avoided.

引用

页数：7

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