Bone health in inflammatory bowel disease

被引：4
作者：
Wei, Hao [1 ,2 ]
Zhao, Yihan [3 ,4 ]
Xiang, Lisha [1 ,2 ]
机构：
[1] Sichuan Univ, West China Hosp, Thorac Oncol Ward, Canc Ctr, Chengdu, Sichuan, Peoples R China
[2] Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu, Sichuan, Peoples R China
[3] Univ Elect Sci & Technol China, Sichuan Acad Med Sci, Dept Cardiol, Chengdu, Peoples R China
[4] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Sch Med, Chengdu, Peoples R China
来源：
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY | 2023年
关键词：
Fracture; inflammatory bowel disease; osteoporosis; osteopenia; pediatric; EXCLUSIVE ENTERAL NUTRITION; QUALITY-OF-LIFE; GROWTH-FACTOR-I; PEDIATRIC CROHNS-DISEASE; POPULATION-BASED COHORT; VITAMIN-D DEFICIENCY; TNF-ALPHA THERAPY; MINERAL DENSITY; ULCERATIVE-COLITIS; EXTRAINTESTINAL MANIFESTATIONS;
D O I：
10.1080/17474124.2023.2248874
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
IntroductionInflammatory bowel disease (IBD) is a chronic disease characterized by the presence of systemic inflammation, manifesting not only as gastrointestinal symptoms but also as extraintestinal bone complications, including osteopenia and osteoporosis. However, the association between IBD and osteoporosis is complex, and the presence of multifactorial participants in the development of osteoporosis is increasingly recognized. Unlike in adults, delayed puberty and growth hormone/insulin-like growth factor-1 axis abnormalities are essential risk factors for osteoporosis in pediatric patients with IBD.Areas coveredThis article reviews the potential pathophysiological mechanisms contributing to osteoporosis in adult and pediatric patients with IBD and provides evidence for effective prevention and treatment, focusing on pediatric patients with IBD. A search was performed from PubMed and Web of Science inception to February 2023 to identify articles on IBD, osteoporosis, pediatric, and fracture risk.Expert opinionA comprehensive treatment pattern based on individualized principles can be used to manage pediatric IBD-related osteoporosis.
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收藏
页码：921 / 935
页数：15
相关论文
共 191 条
[1]   Osteoporosis in inflammatory bowel disease:: effect of calcium and vitamin D with or without fluoride [J].
Abitbol, V ;
Mary, JY ;
Roux, C ;
Soulés, JC ;
Belaiche, J ;
Dupas, JL ;
Gendre, JP ;
Lerebours, E ;
Chaussade, S .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2002, 16 (05) :919-927
[2]   METABOLIC BONE ASSESSMENT IN PATIENTS WITH INFLAMMATORY BOWEL-DISEASE [J].
ABITBOL, V ;
ROUX, C ;
CHAUSSADE, S ;
GUILLEMANT, S ;
KOLTA, S ;
DOUGADOS, M ;
COUTURIER, D ;
AMOR, B .
GASTROENTEROLOGY, 1995, 108 (02) :417-422
[3]   Measurement of vitamin D levels in inflammatory bowel disease patients reveals a subset of Crohn's disease patients with elevated 1,25-dihydroxyvitamin D and low bone mineral density [J].
Abreu, MT ;
Kantorovich, V ;
Vasiliauskas, EA ;
Gruntmanis, U ;
Matuk, R ;
Daigle, K ;
Chen, S ;
Zehnder, D ;
Lin, YC ;
Yang, H ;
Hewison, M ;
Adams, JS .
GUT, 2004, 53 (08) :1129-1136
[4]   Metabolic bone disease in adults with inflammatory bowel disease [J].
Adachi, JD ;
Rostom, A .
INFLAMMATORY BOWEL DISEASES, 1999, 5 (03) :200-211
[5]   Bone, inflammation, and inflammatory bowel disease [J].
Agrawal M. ;
Arora S. ;
Li J. ;
Rahmani R. ;
Sun L. ;
Steinlauf A.F. ;
Mechanick J.I. ;
Zaidi M. .
Current Osteoporosis Reports, 2011, 9 (4) :251-257
[6]   High Risk of Fractures Within 7 Years of Diagnosis in Asian Patients With Inflammatory Bowel Diseases [J].
Ahn, Hyung Jin ;
Kim, Ye-Jee ;
Lee, Ho-Su ;
Park, Jin Hwa ;
Hwang, Sung Wook ;
Yang, Dong-Hoon ;
Ye, Byong Duk ;
Byeon, Jeong-Sik ;
Myung, Seung-Jae ;
Yang, Suk-Kyun ;
Kim, Beom-Jun ;
Park, Sang Hyoung .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2022, 20 (05) :E1022-E1039
[7]   Osteoporosis in Inflammatory Bowel Disease [J].
Ali, Tauseef ;
Lam, David ;
Bronze, Michael S. ;
Humphrey, Mary Beth .
AMERICAN JOURNAL OF MEDICINE, 2009, 122 (07) :599-604
[8]   Effects of Recombinant Human Growth Hormone in Children with Crohn's Disease on the Muscle-Bone Unit: A Preliminary Study [J].
Altowati, Mabrouka A. ;
Shepherd, Sheila ;
McGrogan, Paraic ;
Russell, Richard K. ;
Ahmed, S. Faisal ;
Wong, Sze Choong .
HORMONE RESEARCH IN PAEDIATRICS, 2018, 90 (02) :128-131
[9]   Vertebral fractures in patients with inflammatory bowel disease COMPARED with a healthy population: a prospective case-control study [J].
Angeles Vazquez, Ma ;
Lopez, Enrique ;
Jose Montoya, Ma ;
Giner, Merce ;
Perez-Temprano, Ramon ;
Perez-Cano, Ramon .
BMC GASTROENTEROLOGY, 2012, 12
[10]  
[Anonymous], Adult Positions
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