Deep Learning with a Novel Concoction Loss Function for Identification of Ophthalmic Disease

As ocular computer-aided diagnostic (CAD) tools become more widely accessible, many researchers are developing deep learning (DL) methods to aid in ocular disease (OHD) diagnosis. Common eye diseases like cataracts (CATR), glaucoma (GLU), and age-related macular degeneration (AMD) are the focus of this study, which uses DL to examine their identification. Data imbalance and outliers are widespread in fundus images, which can make it difficult to apply manyDL algorithms to accomplish this analytical assignment. The creation of efficient and reliable DL algorithms is seen to be the key to further enhancing detection performance. Using the analysis of images of the color of the retinal fundus, this study offers a DL model that is combined with a one-of-a-kind concoction loss function (CLF) for the automated identification of OHD. This study presents a combination of focal loss (FL) and correntropy-induced loss functions (CILF) in the proposed DL model to improve the recognition performance of classifiers for biomedical data. This is done because of the good generalization and robustness of these two types of losses in addressing complex datasets with class imbalance and outliers. The classification performance of the DL model with our proposed loss function is compared to that of the baseline models using accuracy (ACU), recall (REC), specificity (SPF), Kappa, and area under the receiver operating characteristic curve (AUC) as the evaluation metrics. The testing shows that the method is reliable and efficient.