Synthesis, Spectral Characterization, and Biological Activities of Some Metal Complexes Bearing an Unsymmetrical Salen-Type Ligand, (Z)-1-(((2-((E)-(2-Hydroxy-6-methoxybenzylidene)amino)phenyl)amino) methylene) Naphthalen-2(1H)-one

被引:3
作者
Nguyen, Quang Trung [1 ]
Thi, Phuong Nam Pham [1 ]
Bui, Quang Do [1 ]
Nguyen, Van Tuyen [1 ]
机构
[1] Vietnam Acad Sci & Technol, Inst Chem, 18 Hoang Quoc Viet, Hanoi, Vietnam
关键词
SCHIFF-BASE LIGANDS; CRYSTAL-STRUCTURES; COPPER(II); NICKEL(II); ELECTRODE; CD(II); ZN(II);
D O I
10.1155/2023/4563958
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An unsymmetrical salen-type Schiff base ligand, (Z)-1-(((2-((E)-(2-hydroxy-6-methoxybenzylidene)amino)phenyl)amino)methylene)naphthalen-2(1H)-one, and its Zn(II), Cu(II), Co(II), Mn(II), and Fe(III) complexes were synthesized and characterized by mass (MS), nuclear magnetic resonance (NMR), infrared (IR), ultraviolet-visible (UV-Vis) spectra, and effective magnetic moments. The thermal analyses of the obtained ligand and metal complexes were conducted by thermogravimetric analysis (TGA). Antimicrobial activity of the unsymmetrical Schiff base ligand and its metal complexes were examined for Staphylococcus aureus as Gram-positive bacteria and Escherichia coli as Gram-negative bacteria. In vitro anticancer property of synthetic compounds was estimated against human cancer cell lines, a subline of Hela tumor cell line (KB), and a human liver cancer cell line (HepG-2) as well.
引用
收藏
页数:8
相关论文
共 44 条
[11]   Transition metal(II) complexes featuring push-pull dianionic Schiff base ligands: synthesis, crystal structure, electrochemical, and NLO studies [J].
Celedon, Salvador ;
Roisnel, Thierry ;
Carrillo, David ;
Ledoux-Rak, Isabelle ;
Hamon, Jean-Rene ;
Manzur, Carolina .
JOURNAL OF COORDINATION CHEMISTRY, 2020, 73 (20-22) :3079-3094
[12]   Nickel(II) and copper(II) complexes of new unsymmetrically-substituted tetradentate Schiff base ligands: Spectral, structural, electrochemical and computational studies [J].
Cisterna, Jonathan ;
Artigas, Vania ;
Fuentealba, Mauricio ;
Hamon, Paul ;
Manzur, Carolina ;
Dorcet, Vincent ;
Hamon, Jean-Rene ;
Carrillo, David .
INORGANICA CHIMICA ACTA, 2017, 462 :266-280
[13]   Electronic structure elucidation in oxidized metal-salen complexes [J].
Clarke, Ryan M. ;
Herasymchuk, Khrystyna ;
Storr, Tim .
COORDINATION CHEMISTRY REVIEWS, 2017, 352 :67-82
[14]   2-methoxy-4-(((5-nitropyridin-2-yl)imino)methyl)phenol Schiff base ligand and its Cu(II) and Zn(II) complexes: synthesis, characterization and biological investigations [J].
Deepika, P. ;
Vinusha, H. M. ;
Begum, Muneera ;
Ramu, Ramith ;
Shirahatti, Prithvi S. ;
Prasad, M. N. Nagendra .
HELIYON, 2022, 8 (06)
[15]   Synthesis, Characterization, Antioxidant, and Antibacterial Studies of Some Metal(II) Complexes of Tetradentate Schiff Base Ligand: (4E)-4-[(2-{(E)-[1-(2,4-Dihydroxyphenyl)ethylidene]amino}ethyl)imino]pentan-2-one [J].
Ejidike, Ikechukwu P. ;
Ajibade, Peter A. .
BIOINORGANIC CHEMISTRY AND APPLICATIONS, 2015, 2015
[16]   Synthesis, characterization, theoretical and molecular docking studies of mixed-ligand complexes of Cu(II), Ni(II), Co(II), Mn(II), Cr(III), UO2(II) and Cd(II) [J].
El-Sonbati, A. Z. ;
Diab, M. A. ;
Morgan, Sh M. ;
Abou-Dobara, M., I ;
El-Ghettany, A. A. .
JOURNAL OF MOLECULAR STRUCTURE, 2020, 1200
[17]   Polymer complexes. LXXVI. Synthesis, characterization, CT-DNA binding, molecular docking and thermal studies of sulfoxine polymer complexes [J].
El-Sonbati, Adel Z. ;
Diab, Mostafa A. ;
Eldesoky, Ahmed M. ;
Morgan, Shaimaa M. ;
Salem, Omnia L. .
APPLIED ORGANOMETALLIC CHEMISTRY, 2019, 33 (05)
[18]   Transition metal salen complexes in bioinorganic and medicinal chemistry [J].
Erxleben, Andrea .
INORGANICA CHIMICA ACTA, 2018, 472 :40-57
[19]   A new copper(II) Schiff base complex containing asymmetrical tetradentate N2O2 Schiff base ligand: Synthesis, characterization, crystal structure and DFT study [J].
Grivani, Gholamhossein ;
Baghan, Sara Husseinzadeh ;
Vakili, Mohammad ;
Khalaji, Aliakbar Dehno ;
Tahmasebi, Vida ;
Eigner, Vaclav ;
Dusek, Michal .
JOURNAL OF MOLECULAR STRUCTURE, 2015, 1082 :91-96
[20]   Unsymmetrical salen nickel (II) complex embracing phenol bridge: X-ray structure, redox investigation, computational calculations, antimicrobial and catalytic activities [J].
Guadouria, Hana-Amira ;
Merzouguia, Moufida ;
Hannachia, Douniazed ;
Alic, Mustapha Ait ;
Ouari, Kamel .
JOURNAL OF MOLECULAR STRUCTURE, 2021, 1242