Synthesis, Spectral Characterization, and Biological Activities of Some Metal Complexes Bearing an Unsymmetrical Salen-Type Ligand, (Z)-1-(((2-((E)-(2-Hydroxy-6-methoxybenzylidene)amino)phenyl)amino) methylene) Naphthalen-2(1H)-one

被引:3
作者
Nguyen, Quang Trung [1 ]
Thi, Phuong Nam Pham [1 ]
Bui, Quang Do [1 ]
Nguyen, Van Tuyen [1 ]
机构
[1] Vietnam Acad Sci & Technol, Inst Chem, 18 Hoang Quoc Viet, Hanoi, Vietnam
关键词
SCHIFF-BASE LIGANDS; CRYSTAL-STRUCTURES; COPPER(II); NICKEL(II); ELECTRODE; CD(II); ZN(II);
D O I
10.1155/2023/4563958
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An unsymmetrical salen-type Schiff base ligand, (Z)-1-(((2-((E)-(2-hydroxy-6-methoxybenzylidene)amino)phenyl)amino)methylene)naphthalen-2(1H)-one, and its Zn(II), Cu(II), Co(II), Mn(II), and Fe(III) complexes were synthesized and characterized by mass (MS), nuclear magnetic resonance (NMR), infrared (IR), ultraviolet-visible (UV-Vis) spectra, and effective magnetic moments. The thermal analyses of the obtained ligand and metal complexes were conducted by thermogravimetric analysis (TGA). Antimicrobial activity of the unsymmetrical Schiff base ligand and its metal complexes were examined for Staphylococcus aureus as Gram-positive bacteria and Escherichia coli as Gram-negative bacteria. In vitro anticancer property of synthetic compounds was estimated against human cancer cell lines, a subline of Hela tumor cell line (KB), and a human liver cancer cell line (HepG-2) as well.
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页数:8
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