Integrating Artificial Intelligence Tools in the Clinical Research Setting: The Ovarian Cancer Use Case

被引:2
|
作者
Sanchez, Lorena Escudero [1 ,2 ,3 ]
Buddenkotte, Thomas [1 ,4 ,5 ,6 ]
Al Sa'd, Mohammad [3 ,7 ]
McCague, Cathal [1 ,2 ,8 ]
Darcy, James [3 ,9 ]
Rundo, Leonardo [1 ,2 ,10 ]
Samoshkin, Alex [11 ]
Graves, Martin J. [1 ,8 ]
Hollamby, Victoria [12 ]
Browne, Paul [13 ]
Crispin-Ortuzar, Mireia [2 ,14 ]
Woitek, Ramona [1 ,2 ,15 ]
Sala, Evis [1 ,2 ,3 ,8 ,16 ,17 ]
Schonlieb, Carola-Bibiane [4 ]
Doran, Simon J. [3 ,9 ]
Oktem, Ozan [18 ]
机构
[1] Univ Cambridge, Dept Radiol, Cambridge CB2 0QQ, England
[2] Li Ka Shing Ctr, Canc Res UK Cambridge Ctr, Cambridge CB2 0RE, England
[3] Natl Canc Imaging Translat Accelerator NCITA Conso, London, England
[4] Univ Cambridge, Dept Appl Math & Theoret Phys, Wilberforce Rd, Cambridge CB3 0WA, England
[5] Univ Hosp Hamburg Eppendorf, Dept Diagnost & Intervent Radiol & Nucl Med, D-20246 Hamburg, Germany
[6] Jung Diagnost GmbH, D-22335 Hamburg, Germany
[7] Imperial Coll, Canc Imaging Ctr, Dept Surg & Canc, London SW7 2AZ, England
[8] Cambridge Univ Hosp NHS Fdn Trust, Cambridge CB2 0QQ, England
[9] Inst Canc Res, Div Radiotherapy & Imaging, London SW7 3RP, England
[10] Univ Salerno, Dept Informat & Elect Engn & Appl Math DIEM, I-84084 Fisciano, Italy
[11] Univ Cambridge, Sch Clin Med, Off Translat Res, Cambridge CB2 0SP, England
[12] Univ Cambridge, Sch Clin Med, Res & Informat Governance, Cambridge CB2 0SP, England
[13] Univ Cambridge, High Performance Comp Dept, Cambridge CB3 0RB, England
[14] Univ Cambridge, Dept Oncol, Cambridge CB2 0XZ, England
[15] Danube Private Univ, Fac Med & Dent, Res Ctr Med Image Anal & Artificial Intelligence M, Dept Med, A-3500 Krems, Austria
[16] Univ Cattolica Sacro Cuore, Dipartimento Sci Radiol Ematol, I-00168 Rome, Italy
[17] Policlin Univ A Gemelli IRCCS, Dipartimento Diagnost Immagini Radioterapia Oncol, I-00168 Rome, Italy
[18] KTH Royal Inst Technol, Dept Math, SE-10044 Stockholm, Sweden
基金
英国惠康基金; 英国工程与自然科学研究理事会;
关键词
artificial intelligence; cancer research; imaging; clinical integration; radiomics; RADIOMICS; PLATFORM;
D O I
10.3390/diagnostics13172813
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Artificial intelligence (AI) methods applied to healthcare problems have shown enormous potential to alleviate the burden of health services worldwide and to improve the accuracy and reproducibility of predictions. In particular, developments in computer vision are creating a paradigm shift in the analysis of radiological images, where AI tools are already capable of automatically detecting and precisely delineating tumours. However, such tools are generally developed in technical departments that continue to be siloed from where the real benefit would be achieved with their usage. Significant effort still needs to be made to make these advancements available, first in academic clinical research and ultimately in the clinical setting. In this paper, we demonstrate a prototype pipeline based entirely on open-source software and free of cost to bridge this gap, simplifying the integration of tools and models developed within the AI community into the clinical research setting, ensuring an accessible platform with visualisation applications that allow end-users such as radiologists to view and interact with the outcome of these AI tools.
引用
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页数:22
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