A strategy for small-molecule RNA degraders

被引：3
|
作者：
Eccleston, Alex
机构：
来源：
NATURE REVIEWS DRUG DISCOVERY | 2023年 / 22卷 / 08期
关键词：
D O I：
10.1038/d41573-023-00112-x
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：621 / 621
页数：1
相关论文
共 50 条
  • [1] A strategy for small-molecule RNA degraders
    Alex Eccleston
    Nature Reviews Drug Discovery, 2023, 22 : 621 - 621
  • [2] Small Molecule RNA Degraders
    Bonet-Aleta, Javier
    Maehara, Tomoaki
    Craig, Benjamin A.
    Bernardes, Goncalo J. L.
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 63 (47)
  • [3] PROTAC small-molecule degraders of AR protein
    Han, Xin
    Wang, Chao
    Qin, Chong
    Xiang, Weiguo
    Fernandez-Salas, Ester
    Yang, Chao-Yie
    Wang, Mi
    Zhao, Lijie
    Xu, Tianfeng
    Stuckey, Jeanne
    Wang, Shaomeng
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 257
  • [4] Breaking down KRAS: small-molecule degraders for cancer therapy
    Kos, Tina
    Saur, Dieter
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2025, 10 (01)
  • [5] PROTAC small-molecule degraders of MDM2 protein
    Aguilar, A.
    Yang, J.
    Li, Y.
    McEachern, D.
    Przybranowski, S.
    Liu, L.
    Yang, C. Y.
    Wang, S.
    EUROPEAN JOURNAL OF CANCER, 2018, 103 : E94 - E94
  • [6] Targeting cancer with small-molecule pan-KRAS degraders
    Popow, Johannes
    Farnaby, William
    Gollner, Andreas
    Kofink, Christiane
    Fischer, Gerhard
    Wurm, Melanie
    Zollman, David
    Wijaya, Andre
    Mischerikow, Nikolai
    Hasenoehrl, Carina
    Prokofeva, Polina
    Arnhof, Heribert
    Arce-Solano, Silvia
    Bell, Sammy
    Boeck, Georg
    Diers, Emelyne
    Frost, Aileen B.
    Goodwin-Tindall, Jake
    Karolyi-Oezguer, Jale
    Khan, Shakil
    Klawatsch, Theresa
    Koegl, Manfred
    Kousek, Roland
    Kratochvil, Barbara
    Kropatsch, Katrin
    Lauber, Arnel A.
    Mclennan, Ross
    Olt, Sabine
    Peter, Daniel
    Petermann, Oliver
    Roessler, Vanessa
    Stolt-Bergner, Peggy
    Strack, Patrick
    Strauss, Eva
    Trainor, Nicole
    Vetma, Vesna
    Whitworth, Claire
    Zhong, Siying
    Quant, Jens
    Weinstabl, Harald
    Kuster, Bernhard
    Ettmayer, Peter
    Ciulli, Alessio
    SCIENCE, 2024, 385 (6715) : 1338 - 1347
  • [7] Discovery of Small-Molecule Degraders for Alpha-Synuclein Aggregates
    Tong, Yichen
    Zhu, Wentao
    Chen, Jian
    Wen, Tianzhi
    Xu, Fang
    Pang, Jiyan
    JOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (12) : 7926 - 7942
  • [8] Small-Molecule Degraders beyond PROTACs-Challenges and Opportunities
    Kastl, Johanna M.
    Davies, Gareth
    Godsman, Eleanor
    Holdgate, Geoffrey A.
    SLAS DISCOVERY, 2021, 26 (04) : 524 - 533
  • [9] Small-Molecule Inhibitors and Degraders Targeting KRAS-Driven Cancers
    Hyun, Soonsil
    Shin, Dongyun
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (22)
  • [10] Small-molecule degraders of cyclin-dependent kinase protein: a review
    Yu, Bin
    Du, Zekun
    Zhang, Yuming
    Li, Zhiyu
    Bian, Jinlei
    FUTURE MEDICINAL CHEMISTRY, 2022, 14 (03) : 167 - 185
12345