Rationale and design of the ABOARD project (A Personalized Medicine Approach for Alzheimer's Disease)

被引:9
|
作者
Dreves, Maria A. E. [1 ,2 ]
van Harten, Argonde [1 ,2 ,3 ]
Visser, Leonie N. C. [1 ,4 ,5 ,6 ]
Rhodius-Meester, Hanneke [1 ,7 ,8 ]
Kohler, Sebastian [9 ]
Kooistra, Minke M. [10 ]
Papma, Janne [11 ,12 ]
Honey, Madison I. J. M. [2 ,3 ]
Blom, Marco M. [10 ]
Smets, Ellen M. A. [4 ,5 ]
de Vugt, Marjolein E.
Teunissen, Charlotte E. [2 ,3 ]
van der Flier, Wiesje [1 ,2 ,9 ,13 ,14 ]
机构
[1] Vrije Univ Amsterdam, Alzheimer Ctr Amsterdam, Neurol, Amsterdam UMC locat VUmc, Amsterdam, Netherlands
[2] Vrije Univ Amsterdam, Amsterdam Neurosci, Amsterdam UMC locat VUmc, Amsterdam, Netherlands
[3] Vrije Univ Amsterdam, Dept Clin Chem, Neurochem Lab, Amsterdam, Netherlands
[4] Univ Amsterdam, Dept Med Psychol, Amsterdam UMC locat AMC, Amsterdam, Netherlands
[5] Univ Amsterdam, Amsterdam Publ Hlth Res Inst, Qual Care, Amsterdam UMC locat AMC, Amsterdam, Netherlands
[6] Karolinska Inst, Div Clin Geriat, Ctr Alzheimer Res, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden
[7] Vrije Univ Amsterdam, Dept Internal Med, Geriat Med Sect, Amsterdam, Netherlands
[8] Oslo Univ Hosp, Dept Geriat Med, Memory Clin, Oslo, Norway
[9] Maastricht Univ, Sch Mental Hlth & Neurosci, Dept Psychiat & Neuropsychol, Maastricht, Netherlands
[10] Alzheimer Nederland, Amersfoort, Netherlands
[11] Erasmus MC Univ Med Ctr, Dept Neurol, Rotterdam, Netherlands
[12] Erasmus MC Univ Med Ctr, Alzheimer Ctr Erasmus MC, Rotterdam, Netherlands
[13] Vrije Univ Amsterdam, Dept Epidemiol & Data Sci, Amsterdam UMC locat VUmc, Amsterdam, Netherlands
[14] Amsterdam UMC locat VUmc, Alzheimer Ctr Amsterdam, PK 1Z44, Boelelaan 1118, NL-1081 HZ Amsterdam, Netherlands
关键词
Alzheimer's disease; diagnosis; patient-orchestrated care; personalized medicine; prediction; prevention; PREVENTION;
D O I
10.1002/trc2.12401
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The key to stopping Alzheimer's disease (AD) lies in the pre-dementia stages, with the goal to stop AD before dementia has started. We present the rationale and design of the ABOARD (A Personalized Medicine Approach for Alzheimer's Disease) project, which aims to invest in personalized medicine for AD. ABOARD is a Dutch public-private partnership of 32 partners, connecting stakeholders from a scientific, clinical, and societal perspective. The 5-year project is structured into five work packages on (1) diagnosis, (2) prediction, (3) prevention, (4) patient-orchestrated care, and (5) communication and dissemination. ABOARD functions as a network organization in which professionals interact cross-sectorally. ABOARD has a strong junior training program "Juniors On Board." Project results are shared with society through multiple communication resources. By including relevant partners and involving citizens at risk, patients, and their care partners, ABOARD builds toward a future with personalized medicine for AD. HighlightsABOARD (A Personalized Medicine Approach for Alzheimer's Disease) is a public-private research project executed by 32 partners that functions as a network organization.Together, the project partners build toward a future with personalized medicine for Alzheimer's disease.Although ABOARD is a Dutch consortium, it has international relevance.ABOARD improves diagnosis, prediction, prevention, and patient-orchestrated care.
引用
收藏
页数:11
相关论文
共 50 条
  • [31] Dimethyl Fumarate as Potential Treatment for Alzheimer's Disease: Rationale and Clinical Trial Design
    Sharkus, Robert
    Thakkar, Richa
    Kolson, Dennis L.
    Constantinescu, Cris S.
    BIOMEDICINES, 2023, 11 (05)
  • [32] The Rationale Behind the New Alzheimer's Disease Conceptualization: Lessons Learned During the Last Decades
    Luis Molinuevo, Jose
    Minguillon, Carolina
    Rami, Lorena
    Domingo Gispert, Juan
    JOURNAL OF ALZHEIMERS DISEASE, 2018, 62 (03) : 1067 - 1077
  • [33] Alzheimer's disease: from basic science to precision medicine approach
    Forloni, Gianluigi
    BMJ NEUROLOGY OPEN, 2020, 2 (02)
  • [34] Study of the effects of mindfulness training on quality of life of patients with Alzheimer's disease and their caregivers (Dyad Mindfulness Project)
    Vespa, Anna
    Fabbietti, Paolo
    Giulietti, Maria Velia
    AGING CLINICAL AND EXPERIMENTAL RESEARCH, 2022, 34 (01) : 65 - 71
  • [35] The Future of Precision Medicine in the Cure of Alzheimer's Disease
    Arafah, Azher
    Khatoon, Saima
    Rasool, Iyman
    Khan, Andleeb
    Rather, Mashoque Ahmad
    Abujabal, Khaled Abdullah
    Faqih, Yazid Abdullilah Hassan
    Rashid, Hina
    Rashid, Shahzada Mudasir
    Ahmad, Sheikh Bilal
    Alexiou, Athanasios
    Rehman, Muneeb U. U.
    BIOMEDICINES, 2023, 11 (02)
  • [36] Voting Ensemble Approach for Enhancing Alzheimer's Disease Classification
    Chatterjee, Subhajit
    Byun, Yung-Cheol
    SENSORS, 2022, 22 (19)
  • [37] Treat Alzheimer's disease by traditional Chinese medicine?
    Sun, Mao-Feng
    Chang, Tung-Ti
    Chen, Kuan-Chung
    Yang, Shun-Chieh
    Chang, Kai-Wei
    Tsai, Tsung-Ying
    Chen, Hsin-Yi
    Tsai, Fuu-Jen
    Lin, Jaung-Geng
    Chen, Calvin Yu-Chian
    MOLECULAR SIMULATION, 2011, 37 (11) : 923 - 931
  • [38] Fluid Candidate Biomarkers for Alzheimer's Disease: A Precision Medicine Approach
    Del Prete, Eleonora
    Beatino, Maria Francesca
    Campese, Nicole
    Giampietri, Linda
    Siciliano, Gabriele
    Ceravolo, Roberto
    Baldacci, Filippo
    JOURNAL OF PERSONALIZED MEDICINE, 2020, 10 (04): : 1 - 34
  • [39] The rationale for deep brain stimulation in Alzheimer’s disease
    Zaman Mirzadeh
    Ausaf Bari
    Andres M. Lozano
    Journal of Neural Transmission, 2016, 123 : 775 - 783
  • [40] Digital biomarkers and sex impacts in Alzheimer's disease management - potential utility for innovative 3P medicine approach
    Harms, Robbert L.
    Ferrari, Alberto
    Meier, Irene B.
    Martinkova, Julie
    Santus, Enrico
    Marino, Nicola
    Cirillo, Davide
    Mellino, Simona
    Solarz, Silvina Catuara
    Tarnanas, Ioannis
    Szoeke, Cassandra
    Hort, Jakub
    Valencia, Alfonso
    Ferretti, Maria Teresa
    Seixas, Azizi
    Chadha, Antonella Santuccione
    EPMA JOURNAL, 2022, 13 (02) : 299 - 313