A multi-omics perspective of CAR T cell therapy

被引：5
|
作者：
Yang, Jingwen [1 ]
Chen, Yamei [1 ]
Han, Leng [1 ,2 ]
机构：
[1] Texas A&M Univ, Inst Biosci & Technol, Ctr Epigenet & Dis Prevent, Houston, TX 77030 USA
[2] Texas A&M Univ, Coll Med, Dept Translat Med Sci, Houston, TX 77030 USA
来源：
CLINICAL AND TRANSLATIONAL MEDICINE | 2023年 / 13卷 / 05期
基金：
美国国家卫生研究院;
关键词：
CART; Omics;
D O I：
10.1002/ctm2.1274
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
As omics technologies, including genomics, epigenomics, transcriptomics, T cell receptor-repertorie profiling, proteomics, metabolomics and microbiomics, have provided valuable insights into CAR T cell therapy, in our recent review, we discuss these multidimensional profiling technologies in CAR T cell research, and their potential to identify tumor-specific antigens and molecular characteristics associated with anti-tumour effects and toxicities.
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页数：3
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